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Immune Reactions in Different Mouse Strains

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Abstract

The responses of immunocompetent cells to thymus-dependent antigen differ in mice of different strains. Immunization stimulated phagocytic activity of peritoneal macrophages in CBA/CaLac, DBA/2, and BALB/c mice and suppressed it in CC57W mice. By the formation of antibody-producing cells in the spleen in response to thymus-dependent antigen DBA/2 and CBA/CaLac mice can be classified as high responders, BALB/c mice as medium-responders, and C57Bl/6 and CC57W mice as low responders.

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Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Siberian Branch of Russian Academy of Medical Sciences, Russia

    N. V. Masnaya, A. A. Churin, O. S. Borsuk & E. Yu. Sherstoboev

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  1. N. V. Masnaya
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  2. A. A. Churin
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  3. O. S. Borsuk
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  4. E. Yu. Sherstoboev
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Masnaya, N.V., Churin, A.A., Borsuk, O.S. et al. Immune Reactions in Different Mouse Strains. Bulletin of Experimental Biology and Medicine 134, 376–378 (2002). https://doi.org/10.1023/A:1021916500286

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  • DOI: https://doi.org/10.1023/A:1021916500286

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