Skip to main content
Log in

Non-parametric Hypothesis Testing and Confidence Intervals with Doubly Censored Data

  • Published:
Lifetime Data Analysis Aims and scope Submit manuscript

Abstract

The non-parametric maximum likelihood estimator (NPMLE) of the distribution function with doubly censored data can be computed using the self-consistent algorithm (Turnbull, 1974). We extend the self-consistent algorithm to include a constraint on the NPMLE. We then show how to construct confidence intervals and test hypotheses based on the NPMLE via the empirical likelihood ratio. Finally, we present some numerical comparisons of the performance of the above method with another method that makes use of the influence functions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • M. N. Chang and G. L. Yang, “Strong consistency of a non-parametric estimator of the survival function with doubly censored data,” Ann. Statist. vol. 15, pp. 1536–1547, 1987.

    Google Scholar 

  • M. N. Chang, “Weak convergence of a self-consistent estimator of the survival function with doubly censored data,” Ann. Statist. vol. 18, pp. 391–404, 1990.

    Google Scholar 

  • A. P. Dempster, N. M. Laird, and D. B. Rubin, “Maximum likelihood from incomplete data via the EM algorithm with discussion,” J. Roy. Statist. Soc., Ser. vol. B 39, pp. 1–38, 1977.

    Google Scholar 

  • R. Gentleman and R. Ihaka, “R: A Language for data analysis and graphics,” J. of Computational and Graphical Statistics vol. 5, pp. 299–314, 1996.

    Google Scholar 

  • B. Efron, “The two sample problem with censored data,” Proc. Fifth Berkeley Symp. Math. Statist. Probab. vol. 4, pp. 831–883, 1967.

    Google Scholar 

  • R. Gill, “Non-and semi-parametric maximum likelihood estimator and the Von Mises method (I),” Scand. J. Statist. vol. 16, pp. 97–128, 1989.

    Google Scholar 

  • B. A. Hamberg, H. C. Kraemer, and W. Jahnke, “A hierarchy of drug use in adolescence behavioral and attitudinal correlates of substantial drug use,” American Journal of Psychiatry vol. 132, pp. 1155–1163, 1975.

    Google Scholar 

  • E. Kaplan and P. Meier, “Non-parametric estimator from incomplete observations,” J. Amer. Statist. Assoc. vol. 53, pp. 457–481, 1958.

    Google Scholar 

  • S. Murphy and Van der Vaart, “Semi-parametric likelihood ratio inference,” Ann. Statist. vol. 25, pp. 1471–1509,1997.

    Google Scholar 

  • P. A. Mykland and J. J. Ren, “Algorithms for Computing Self-Consistent and Maximum Likelihood Estimators with Doubly Censored Data,” Ann. Statist. vol. 24, pp. 1740–1764, 1996.

    Google Scholar 

  • A. Owen, “Empirical likelihood ratio confidence intervals for a single functional,” Biometrika vol. 75, pp. 237–249, 1988.

    Google Scholar 

  • A. Owen, Empirical Likelihood, Chapman & Hall: London, 2001.

    Google Scholar 

  • W. Press, S. Teukolsky, W. Vetterling, and B. Flannery, Numerical Recipes in C: The Art of Scientific Computing, Cambridge Univ. Press, Chapter 18.1, pp. 791–794, 1993.

  • B. W. Turnbull, “Non-parametric estimation of a survivorship function with doubly censored data,” J. Amer. Statist. Assoc. vol. 69, pp. 169–173, 1974.

    Google Scholar 

  • B. W. Turnbull, “The empirical distribution function with arbitrarily grouped, censored and truncated data,” J. R. Statis. Soc. vol. B 38, pp. 290–295, 1976.

    Google Scholar 

  • B. W. Turnbull and Weiss, “A likelihood aatio statistic for testing goodness of fit with randomly censored data,” Biometrics vol. 34, pp. 367–375, 1978.

    Google Scholar 

  • W. Y. Tsai and J. Crowley, “A large sample study of generalized maximum likelihood estimator from incomplete data via self-consistency,” Ann. Statist. vol. 13, no.4, pp. 1317–1334, 1985.

    Google Scholar 

  • Y. Zhan and J. Wellner, “A hybrid algorithm for computation of the NPMLE from censored data,” J. Amer. Statist. Assoc. vol. 92, pp. 945–959, 1999.

    Google Scholar 

  • M. Zhou, http://lib.stat.cmu.edu/s/d009newr, 1995.

  • M. Zhou, L. Lee, and K. Chen, http://cran.r-project.org as contributed package dblcens, 2001.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chen, K., Zhou, M. Non-parametric Hypothesis Testing and Confidence Intervals with Doubly Censored Data. Lifetime Data Anal 9, 71–91 (2003). https://doi.org/10.1023/A:1021834206327

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1021834206327

Navigation