Abstract
A method was developed for the synthesis of 2-oxo-4-phenyl-2,3-dihydro-9H-pyrimido[4,5-b]indole as well as of 2-chloro- and 2-nitramino-4-phenylpyrimido[4,5-b]indoles. The replacement of the chlorine atom in 2-chloropyrimidoindole gave rise to a number of its functional derivatives (morpholino, azido, and cyano). The reaction of 2-chloro-substituted pyrimidoindole with hydrazine hydrate and catalytic hydrogenation of 2-nitraminopyrimidoindole were studied.
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Borovik, V.P., Shkurko, O.P. Synthesis of functional 2-substituted 4-phenyl-9H-pyrimido[4,5-b]indoles. Russian Chemical Bulletin 51, 2129–2133 (2002). https://doi.org/10.1023/A:1021688616234
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DOI: https://doi.org/10.1023/A:1021688616234