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The Regulatory Role of the Hfq Protein in Bacterial Cells

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Abstract

Hfq (HF1) is a polyfunctional translational regulator of numerous bacterial mRNAs. Its physico-chemical properties, possible mechanisms regulating bacterial translation, and the effect of Hfq on transcription of several mRNAs are considered. A similarity of Hfq and eukaryotic mRNA splicing proteins is discussed. Data are reviewed on the roles of Hfq in poly(A) metabolism and formation of the bacterial nucleoid and on the Hfq interaction with untranslated regulatory RNAs.

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  1. Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia

    I. M. Vassilieva & M. B. Garber

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  1. I. M. Vassilieva
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  2. M. B. Garber
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Vassilieva, I.M., Garber, M.B. The Regulatory Role of the Hfq Protein in Bacterial Cells. Molecular Biology 36, 785–791 (2002). https://doi.org/10.1023/A:1021621623503

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