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Effect of Bioresonance Therapy on Antioxidant System in Lymphocytes in Patients with Rheumatoid Arthritis


We measured activities of superoxide dismutase, catalase, and glutathione peroxidase and content of nonprotein thiol groups (reduced glutathione) in blood lymphocytes from patients with rheumatoid arthritis before and during bioresonance therapy. The state of the antioxidant system in lymphocyte from patients receiving standard pharmacotherapy was characterized by activation of the key antioxidant enzymes and decreased content of thiol groups. Bioresonance therapy increased the content of thiol groups and normalized activities of superoxide dismutase and glutathione peroxidase. However, catalase activity remained above the control. Changes in the lymphocyte antioxidant system indicate that bioresonance therapy activates nonspecific protective mechanisms in patients with rheumatoid arthritis.

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  1. M. V. Bilenko, Ischemic and Reperfusion Damages to Organs [in Russian], Moscow (1989).

  2. Bioresonance Therapy (Methodical Recommendations No. 2000/74) [in Russian], Moscow (2000).

  3. A. I. Karpishchenko, V. V. Smirnov, S. I. Glushkov, and V. L. Pastushenkov, Klin. Lab. Diagn., No. 12, 41–42 (1997).

  4. B. I. Islamov, V. A. Funtikov, R. V. Bobrovskii, and Yu. V. Gotovskii, Byull. Eksp. Biol. Med., 128,No. 11, 525–528 (1999).

    Google Scholar 

  5. T. A. Lisitsyna, M. M. Ivanova, and A. D. Durnev, Vestn. Ros. Akad. Med. Nauk, No. 12, 15–19 (1996).

  6. E. B. Men'shikova and N. K. Zenkov, Usp. Sovr. Biol., 113, 442–455 (1993).

    Google Scholar 

  7. A. V. Samokhin and Yu. V. Gotovskii, Practical Electropuncture by the Method of R. Foll [in Russian], Moscow (1997).

  8. V. V. Sokolovskii, Vopr. Med. Khimii, No. 6, 2 (1988).

  9. K. Bauerova and S. Bezek, Gen. Physiol. Biophys., 18, 15–20 (1999).

    Google Scholar 

  10. C. Beauchamp and I. Fridovich, Anal. Biochem., 44, 276–287 (1971).

    Google Scholar 

  11. J. M. McCord, Science, 185,No. 150, 529–531 (1974).

    Google Scholar 

  12. Methods of Enzymatic Analysis, Eds. H. U. Bergmeyer et al., 3rd Ed., Vol. 3, pp. 276–281.

  13. M. Nivsarka, Biochem. Biophys. Res. Commun., 270, 714–716 (2000).

    Google Scholar 

  14. M. Rister, K. Bauermeister, U. Gravert, and E. Gladtke, Lancet, 1,No. 8073, 1094 (1978).

    Google Scholar 

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Islamov, B.I., Balabanova, R.M., Funtikov, V.A. et al. Effect of Bioresonance Therapy on Antioxidant System in Lymphocytes in Patients with Rheumatoid Arthritis. Bulletin of Experimental Biology and Medicine 134, 248–250 (2002).

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  • rheumatoid arthritis
  • lymphocyte antioxidant system
  • bioresonance therapy