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Preparation and characterization of novel silica-butyrylchitosan hybrid biomaterials*

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Abstract

Novel silica-butyrylchitosan hybrid biomaterials were produced by a sol–gel technique, using butyrylchitosan as the organic species incorporated into the silicon alkoxide (TEOS) based network. 3-acryloxypropyl trimethoxysilane (MPTMS) was used effectively to combine the organic and inorganic species to form uniform hybrid biomaterials. All the samples made were in the form of thin, flexible films with transparent clarity. The blood-clotting and platelet adhesion assay confirmed that these hybrid biomaterials displayed potential good blood compatibility.

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Authors and Affiliations

  1. Department of Polymer Science and Engineering, Nanjing University, Nanjing, 210093 People's, Republic of China

    A. P. Zhu, Z. Zhang & J. Shen

Authors
  1. A. P. Zhu
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  2. Z. Zhang
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  3. J. Shen
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Zhu, A.P., Zhang, Z. & Shen, J. Preparation and characterization of novel silica-butyrylchitosan hybrid biomaterials*. Journal of Materials Science: Materials in Medicine 14, 27–31 (2003). https://doi.org/10.1023/A:1021593218662

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  • DOI: https://doi.org/10.1023/A:1021593218662

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