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New method for trimethylsilylation of hydroxy-containing compounds. Synthesis of persilylated ecdysteroids and carbohydrates

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Russian Chemical Bulletin Aims and scope

Abstract

A new method was developed for trimethylsilylation of alcohols by the reactions with (trifluoromethyl)trimethylsilane in the presence of tetrabutylammonium fluoride. The reactions of ecdysteroids (20-hydroxyecdysone, its 20,22-mono- and 2,3:20,22-diacetonides, and polypodine B) and carbohydrates (D-gluco-, D-galacto-, and D-xylopyranoses) afforded the corresponding persilylated derivatives.

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Authors and Affiliations

  1. Bashkortostan Republic Academy of Sciences and Ufa Research Center of the Russian Academy of Sciences, Institute of Petrochemistry and Catalysis, 141 prosp. Oktyabrya, 450075, Ufa, Russian Federation

    V. N. Odinokov, R. G. Savchenko, S. R. Nazmeeva, I. V. Galyautdinov & L. M. Khalilov

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  1. V. N. Odinokov
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  2. R. G. Savchenko
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  3. S. R. Nazmeeva
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  4. I. V. Galyautdinov
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  5. L. M. Khalilov
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Odinokov, V.N., Savchenko, R.G., Nazmeeva, S.R. et al. New method for trimethylsilylation of hydroxy-containing compounds. Synthesis of persilylated ecdysteroids and carbohydrates. Russian Chemical Bulletin 51, 1937–1939 (2002). https://doi.org/10.1023/A:1021377207689

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  • DOI: https://doi.org/10.1023/A:1021377207689

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