Abstract
In aqueous medium etiolated wheat seedlings release superoxide anion (\(O_2^{_ \cdot ^ -}\)). Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by \(O_2^{_ \cdot ^ -}\) formation. This suggests that under certain conditions BHT behaves as a prooxidant. A natural antioxidant, superoxide dismutase (SOD), and also a wound healing preparation, emulsified denatured placenta (EDP), do not exhibit the prooxidant properties. In contrast to BHT, they reduce \(O_2^{_ \cdot ^ -}\) production by the etiolated wheat seedling system.
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Smirnova, E.G., Lyubimov, Y.I., Malinina, T.G. et al. Ionol (BHT) Produces Superoxide Anion. Biochemistry (Moscow) 67, 1271–1275 (2002). https://doi.org/10.1023/A:1021357506703
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DOI: https://doi.org/10.1023/A:1021357506703