Abstract
Reversed-phase high performance liquid chromatography (Separon SGX CN, UV detection at 254~nm and water as mobile phase) was applied to thestudy of the host–guest complexation ofp-H-37-(2-carboxy-methyloxy)-calix-[6]-arene (1) and p-sulphonato-37-(2-carboxy-methyloxy)-calix-[6]-arene (2)with 15 amino acids in the mobile phase. It was established that the formation ofthe inclusion complexes results in changes in the retention times and capacity factorsof amino acids. Stability constants of the complexes were determined. The variations instability constant values may be explained in terms of the different interactions, whichmay occur between amino acids and 1 and 2.
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Kalchenko, O.I., Da Silva, E. & Coleman, A.W. Determination of the Stability Constants of Inclusion Complexes of p-H-37-(2-carboxy-methyloxy)-calix-[6]-arene and p-sulphonato-37-(2-carboxy-methyloxy)-calix-[6]-arene with 15 Amino acids by RP-HPLC. Journal of Inclusion Phenomena 43, 305–310 (2002). https://doi.org/10.1023/A:1021203505307
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DOI: https://doi.org/10.1023/A:1021203505307