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Effects of Horseradish Root on Functional Activity of Phagocytes, Total Blood Cell Count, and State of the Liver in Mice with Experimental Leprosy

Abstract

Therapy of experimental leprosy with dried and grated horseradish root administered perorally in a dose of 300 mg/kg mixed food and treatment with purified horseradish peroxidase increased myeloperoxidase activity of blood neutrophils, enhanced antimicrobial functions of phagocytes, decreased leukocytosis, normalized total blood cell count, and produced no adverse effects on the functional state of the liver in mice.

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REFERENCES

  1. 1.

    N. I. Bakhov, L. Z. Aleksandrova, and V. N. Titov, Lab. Delo, No. 6, 3–12 (1988).

  2. 2.

    Laboratory Studies in Clinical Practice, Ed. V. V. Men'shikov [in Russian], Moscow (1987).

  3. 3.

    A. K. Maslov and O. V. Kalyanina, Byull. Eksp. Biol. Med., 129,No. 5, 571–573 (2000).

    Google Scholar 

  4. 4.

    A. K. Maslov and S. A. Luzhnova, Ibid., 130,No. 7, 83–87 (2000).

    Google Scholar 

  5. 5.

    A. K. Maslov, S. A. Luzhnova, and O. V. Kalyanina, Ibid., 132,No. 11, 551–553 (2001).

    Google Scholar 

  6. 6.

    Laboratory Techniques for Leprosy, Geneva (1987).

  7. 7.

    C. C. Shepard, J. Exp. Med., 112, 445–454 (1960).

    Google Scholar 

  8. 8.

    C. C. Shepard and D. H. McRae, Int. J. Lepr., 36, 78–82 (1968).

    Google Scholar 

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Maslov, A.K., Luzhnova, S.A. & Kalyanina, O.V. Effects of Horseradish Root on Functional Activity of Phagocytes, Total Blood Cell Count, and State of the Liver in Mice with Experimental Leprosy. Bulletin of Experimental Biology and Medicine 134, 156–158 (2002). https://doi.org/10.1023/A:1021136331466

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  • experimental leprosy
  • horseradish root
  • dynamics of M. leprae reproduction
  • phagocyte activity
  • hemogram