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Interaction between the Cholinergic and Purinergic Control of Transmitter Release in the Neuromuscular Junction

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Abstract

The interaction between the cholinergic and purinergic receptors in the frog neuromuscular junction was studied using a standard microelectrode technique. The inhibitory action of an acetylcholine analog, carbachol, on transmitter release virtually disappeared when the releasing machinery was initially blocked by adenosine, indicating the existence of a functional cross-talk between the purinergic and cholinergic receptors.

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Authors and Affiliations

  1. Kazan Institute of Biochemistry and Biophysics, Republic of Tatarstan, Russia

    A. V. Shakirzyanova

  2. Kazan State Medical University, Republic of Tatarstan, Russia

    R. A. Giniatullin

Authors
  1. A. V. Shakirzyanova
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  2. R. A. Giniatullin
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Correspondence to A. V. Shakirzyanova.

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Shakirzyanova, A.V., Giniatullin, R.A. Interaction between the Cholinergic and Purinergic Control of Transmitter Release in the Neuromuscular Junction. Neurophysiology 34, 224–225 (2002). https://doi.org/10.1023/A:1020732123247

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  • DOI: https://doi.org/10.1023/A:1020732123247

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