Skip to main content
Log in

Hemopoietic and Lymphoid Organs in AKR/JY Mice with Thymic Lymphoma

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Cytological and histological studies of the thymus, bone marrow, peripheral blood, spleen, and lymph nodes in 6-9-month-old AKR/JY mice showed that the risk of thymic lymphoma in these animals increased with age. Generalization of the tumor process was observed in mice aged over 8 months and first involved the spleen, then the lymph nodes, bone marrow, and liver. A case of primary lymphoma in the spleen was detected.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. Z. K. Blandova, V. A. Dushkin, A. M. Malashenko, and E. F. Schmidt, Laboratory Animal Strains for Biomedical Studies [in Russian], Moscow (1983).

  2. S. A. Kozlov, V. N. Pan'kov, S. A. Konyshev, et al., Gematol. Transfuziol., 42,No. 2, 19–22 (1997).

    Google Scholar 

  3. L. A. Kosnyreva, Regularities of Hemopoiesis Regulation in AKR/JY Mice during the Preuleukemic Period, Abstract of Cand. Med. Sci. Dissertation, Tomsk (1999).

  4. N. I. Kochergina and A. A. Yarilin, Eksp. Onkol., 8,No. 2, 57–60 (1986).

    Google Scholar 

  5. G. F. Lakin, Biometry [in Russian], Moscow (1980).

  6. I. A. Lisukov, I. G. Tsyrlova, and V. A. Kozlov, Eksp. Onkol., No. 1, 71–73 (1986).

  7. N. A. Probatova, N. N. Tupitsyn, and E. V. Fleishman, Arkh. Patol., No. 4, 61–71 (1998).

  8. A. I. Svirnovskii, T. V. Shimanskaya, A. V. Bakun, et al., Pressing Problems in Standardization of Laboratory Animals for Biomedical Studies [in Russian], Moscow (1988), pp. 152–154.

  9. Handbook of Laboratory Methods of Investigation, Ed. V. V. Men'shikov [in Russian], Moscow (1987).

  10. I. G. Tsyrlova, Vestn. Akad. Med. Nauk SSSR, No. 12, 34–39 (1991).

  11. J. M. Angel, D. C. Morisot, and E. R. Richie, J. Natl. Cancer Inst., 8,No. 21, 1652–1655 (1989).

    Google Scholar 

  12. A. Barker and S. Waksal, Cell Immunol., 12,No. 1, 140–149 (1974).

    Google Scholar 

  13. M. Bortin and R. Truitt, Biomedicine, 26,No. 3, 309–312 (1977).

    Google Scholar 

  14. L. Gross, Proc. Soc. Exp. Biol. Med., 76,No. 1, 27–30 (1951).

    Google Scholar 

  15. E. F. Hays, G. C. Bristol, J. P. Lugo, and X. F. Wang, Exp. Haematol., No. 7, 1116–1121 (1989).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Karpova, G.V., Fomina, T.I., Abramova, E.V. et al. Hemopoietic and Lymphoid Organs in AKR/JY Mice with Thymic Lymphoma. Bulletin of Experimental Biology and Medicine 134, 69–72 (2002). https://doi.org/10.1023/A:1020669007938

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1020669007938

Navigation