Abstract
Cytological and histological studies of the thymus, bone marrow, peripheral blood, spleen, and lymph nodes in 6-9-month-old AKR/JY mice showed that the risk of thymic lymphoma in these animals increased with age. Generalization of the tumor process was observed in mice aged over 8 months and first involved the spleen, then the lymph nodes, bone marrow, and liver. A case of primary lymphoma in the spleen was detected.
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Karpova, G.V., Fomina, T.I., Abramova, E.V. et al. Hemopoietic and Lymphoid Organs in AKR/JY Mice with Thymic Lymphoma. Bulletin of Experimental Biology and Medicine 134, 69–72 (2002). https://doi.org/10.1023/A:1020669007938
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DOI: https://doi.org/10.1023/A:1020669007938