References
Rossi MA. Pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans. J Hypertension 1998;16:1031–1041.
Bishop JE, Greenbaum R, Gibson DG, Yacoub M, Laurent GJ. Enhanced deposition of predominantly type I collagen in myocardial disease. J Mol Cell Cardiol 1990;22:1157–1165.
Wei S, Chow LTC, Shum OL, Qin L, Sanderson JE. J Cardiac Failure 1999;5:117–126.
Weber KT. Targeting pathological remodeling. Concepts of cardioprotection and reparation. Circulation 2000;102:1342–1345.
Bishop JE, Lindahl G. Regulation of cardiovascular collagen synthesis by mechanical load. Cardiovasc Res 1999;42:27–44.
Mann DL, Spinnale FG. Activation of matrix metalloproteinases in the failing human heart: Breaking the tie that binds. Circulation 1998;98:1699–1702.
Sanderson JE, Lai KB, Shum IOL, Wei S, Chow LTC. Transforming growth factor-? expression in dilated cardiomyopathy. Heart 2001;86:701–702.
Silvestre JR, Heymes C, Oubenaissa A, et al. Activation of cardiac aldosterone production in rat myocardial infarction: Effect of angiotensin II receptor blockade and role in cardiac fibrosis. Circulation 1999;99:2694–2701.
Brilla CG, Funck RC, Rupp H. Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease. Circulation 2000;102:1388–1393.
Wei S, Chow LTC, Sanderson JE. Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction. J Am Coll Cardiol 2000;36:276–281.
Sia YT, Parker TG, Tsoporis JN, Liu P, Adam A, Rouleau JL. Long-term effects of carvedilol on left ventricular function, remodeling, and expression of cardiac cytokines after large myocardial infarction in the rat. J Cardiovasc Pharm 2002;39:73–87.
Weber KT, Brilla CG. Pathological hypertrophy and cardiac interstitium: fibrosis and rennin-angiotensin-aldosterone system. Circulation 1991;83:1849–1865.
Sanderson JE, Cockram CS, Yu CM, Campbell SE, Weber KT. Myocardial fibrosis and hyperaldosteronism. Eur Heart J 1996;17:1761–1762.
Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 1999;341:709–717.
Cittadini A, Casaburi C, Monti MG, et al. Effects of canrenone on myocardial reactive fibrosis in a rat model of postinfarction heart failure. Cardiovasc Drugs Ther 2002;16(3):195–202.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sanderson, J.E. New Treatments for Myocardial Fibrosis. Cardiovasc Drugs Ther 16, 181–182 (2002). https://doi.org/10.1023/A:1020636002954
Issue Date:
DOI: https://doi.org/10.1023/A:1020636002954