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Therapy of Peptic Ulcer with Semax Peptide

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Abstract

Experiments used is combination with traditional preparations (omeprasole, de-nol, and solcoseril), Semax peptide (Met-Glu-His-Phe-Pro-Gly-Pro) possessing nootropic and neuroprotective activity significantly promoted ulcer healing in patients with refractory peptic ulcers. On day 14 of treatment ulcer healing was observed in 89.5% patients receiving intranasal Semax (1% solution, 2-4 drops 3 times a day for 10 days) vs. 30.8% in the control group. Clinical studies of antiulcer activity of Semax in different combinations with usual antiulcer drugs are needed.

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Authors and Affiliations

  1. Medical Center of President's Administration, Central Clinical Hospital, M. V. Lomonosov Moscow State University; Institute of Molecular Genetics, Russian Academy of Sciences, Moscow

    I. O. Ivanikov, M. E. Brekhova, G. E. Samonina, N. F. Myasoedov & I. P. Ashmarin

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  1. I. O. Ivanikov
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  2. M. E. Brekhova
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  3. G. E. Samonina
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  4. N. F. Myasoedov
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  5. I. P. Ashmarin
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Ivanikov, I.O., Brekhova, M.E., Samonina, G.E. et al. Therapy of Peptic Ulcer with Semax Peptide. Bulletin of Experimental Biology and Medicine 134, 73–74 (2002). https://doi.org/10.1023/A:1020621124776

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  • DOI: https://doi.org/10.1023/A:1020621124776

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