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Assessment of the Dominant Abnormal Form Is Useful for Predicting the Outcome of Intracytoplasmic Sperm Injection in the Case of Severe Teratozoospermia

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Abstract

Purpose: Our purpose was to investigate the relation between the dominant sperm anomaly and sperm morphology and the outcome of intracytoplasmic sperm injection (ICSI).

Methods: Two hundred ninety-five patients who underwent a total of 181 cycles of in vitro fertilization (n = 168) and/or 217 cycles of ICSI (n = 177) between July 1995 and May 1997 at Keio University Hospital were investigated.

Results: The rates of fertilization and pregnancy were 63.3 and 27.8%, respectively, in ICSI cycles with ≤4% normal forms. When the percentage of strictly normal morphology was ≤4, the fertilization rate was lower in the case of severely tapered head (13.0%; n = 4) than in the cases of other deformities in ICSI. The acrosomal defect made no difference in the fertilization rate with ICSI.

Conclusions: The predominant abnormal form affects the ICSI outcome in the case of ≤4% normal forms.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, 160-8582, Tokyo, Japan

    Yoshiko Osawa, Kou Sueoka, Soukichi Iwata, Masami Shinohara, Noriko Kobayashi, Nadaki Kuji & Yasunori Yoshimura

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  1. Yoshiko Osawa
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  2. Kou Sueoka
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  3. Soukichi Iwata
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  4. Masami Shinohara
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  5. Noriko Kobayashi
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  6. Nadaki Kuji
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  7. Yasunori Yoshimura
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Osawa, Y., Sueoka, K., Iwata, S. et al. Assessment of the Dominant Abnormal Form Is Useful for Predicting the Outcome of Intracytoplasmic Sperm Injection in the Case of Severe Teratozoospermia. J Assist Reprod Genet 16, 436–442 (1999). https://doi.org/10.1023/A:1020573609836

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  • DOI: https://doi.org/10.1023/A:1020573609836

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