Abstract
Purpose: Our purpose was to investigate the influence of previous tuberculous epididymitis in patients with obstructive azoospermia on the outcome of sperm retrieval and intracytoplasmic sperm injection (ICSI).
Methods: Eighty-eight cycles of ICSI were performed in 44 patients with obstructive azoospermia; 16 cycles (7 patients) with tuberculous obstructive azoospermia and 72 cycles (37 patients) with nontuberculous obstructive azoospermia.
Results: The rates of fertilization and embryo cleavage were comparable, and there was no significant difference in the clinical pregnancy rate per fresh transfer between the two groups. The rates of embryo implantation and clinical miscarriage were also comparable.
Conclusions: Embryo quality and pregnancy outcome in sperm retrieval and ICSI were comparable in both the tuberculous and the nontuberculous obstructive azoospermia patients. Although there was a preponderance of testicular sperm used in the tuberculous obstructive azoospermia group, our results suggest that previous tuberculous epididymitis in patients with obstructive azoospermia does not affect the outcome of sperm retrieval and ICSI.
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REFERENCES
Schlegel PN, Goldstein M: Microsurgical vasoepididymostomy: Refinements and results. J Urol 1993;50:1165-1168
Temple-Smith PD, Southwick GJ, Yates CA, Trounson AO, Kretser DM: Human pregnancy by in vitro fertilization using sperm aspirated from epididymis. J Vitro Fert Embryo Transfer 1985;2:119-122
Silver SJ, Balmaceda J, Borrero C, Ord T, Asch R: Pregnancy with sperm aspiration from the proximal head of the epididymis: A new treatment for congenital absence of the vas deferens. Fertil Steril 1988;50:525-528
Hirsch AV, Mills C, Bekir J: Factors influencing the outcome of in vitro fertilization with epididymal spermatozoa in irreversible obstructive azoospermia. Hum Reprod 1994;9:1710-1716
Palermo G, Joris H, Devroey P, Van Steirteghem AC: Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 1992;340(8810):17-18
Van Steirteghem AC, Nagy Z, Joris H, Liu J, Staessen C, Smitz J, Wisanto A, Devroey P: High fertilization and implantation rates after intracytoplasmic sperm injection. Hum Reprod 1993;8:1061-1066
Silber SJ, Nagy ZP, Liu J, Godoy H, Devroey P, Van Steirteghem AC: Conventional in vitro fertilization versus intracytoplasmic sperm injection for patients requiring microsurgical sperm aspiration. Hum Reprod 1994;9:1705-1709
Tournaye H, Devroey P, Liu J: Microsurgical sperm aspiration and intracytoplasmic sperm injection: A new effective approach to infertility as a result of congenital bilateral agenesis of vas deferens. Fertil Steril 1994;61:1045-1051
Gurgan T, Urman B, Yarali H: Results of in vitro fertilization and embryo transfer in women with infertility due to genital tuberculosis. Fertil Steril 1996;65:367-370
Lee HY: A 20-year experience with epididymovasostomy for pathologic epididymal obstruction. Fertil Steril 1987;47:487-491
Kim SH, Pollack HM, Cho KS, Pollack MS, Han MC: Tuberculous epididymitis and epididymo-orchitis: Sonographic findings. J Urol 1993;150:81-84
Kim SH, Jee BC, Chung KN, Kim HS, Ryu BY, Oh SK, Moon SY, Lee JY, Chang YS: Prevention of multifetal pregnancy in in vitro fertilization and embryo transfer: Significance of embryo grading and cumulative embryo score. Korean J Obstet Gynecol 1995;38:2333-2346
Steer CV, Mills, CL, Tan SL, Campbell S, Edwards RG: The cumulative embryo score: a predictive embryo scoring technique to select the optimal number of embryos to transfer in an in vitro fertilization and embryo transfer programme. Hum Reprod 1992;7:117-119
Varma TR: Genital tuberculosis and subsequent fertility. Int J Gynaecol Obstet 1991;35:1-11
Marcus SF, Rizk B, Fountain S, Brinsden P: Tuberculous infertility and in vitro fertilization. Am J Obstet Gynecol 1994;171:1593-1596
Tsirigotis M, Pelekanos M, Yazdani N, Boulos A, Foster C, Craft IL: Simplified sperm retrieval and intracytoplasmic sperm injection in patients with azoospermia. Br J Urol 1995;76:765-768
Kahraman S, Özgür S, Alatas C, Aksoy S, Balaban B, Evrenkaya T, Nuhoglu A, Tasdemir M, Biberoglu K, Schoysman R, Vanderzwalmen P, Nijs M: High implantation and PRs with testicular sperm extraction and intracytoplasmic sperm injection in obstructive and non-obstructive azoospermia. Hum Reprod 1996;11:673-676
Craft IL, Khalifa Y, Boulos A, Pelekanos M, Foster C, Tsirigotis M: Factors influencing the outcome of in vitro fertilization with percutaneous aspirated epididymal spermatozoa and intracytoplasmic sperm injection in azoospermic men. Hum Reprod 1995;10:1791-1794
Patrizio P, Silber SJ, Ord T, Marello E, Balmaceda JP, Asch RH: Replacement of frozen embryos generated from epididymal sperm: The first two pregnancies. Hum Reprod 1992;7:652-653
Palermo GD, Schlegel PN, Hariprashad JJ, Ergn B, Mielnik A, Zaninovic N, Veeck LL, Rosenwaks Z: Fertilization and pregnancy outcome with intracytoplasmic sperm injection for azoospermic men. Hum Reprod 1999;14:741-748
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Moon, S.Y., Kim, S.H., Jee, B.C. et al. The Outcome of Sperm Retrieval and Intracytoplasmic Sperm Injection in Patients with Obstructive Azoospermia: Impact of Previous Tuberculous Epididymitis. J Assist Reprod Genet 16, 431–435 (1999). https://doi.org/10.1023/A:1020521625765
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DOI: https://doi.org/10.1023/A:1020521625765