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Synthesis of Polyfunctional Terpenoids from Monoterpenes and N-(2-Mercaptopropyonyl)glycine

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Abstract

Addition of N-(2-mercaptopropyonyl)glycine to (+)-limonene or (-)-β-pinene in the presence of a Lewis acid involves the mercapto group; simultaneously, the carboxyl function is esterified by ethanol used as solvent. Both reactions give rise to a terpenoid of the menthane structure, which contains, along with a sulfide group, a peptide fragment promising in terms of biologic activity, as well as an ester group.

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Authors and Affiliations

  1. Kurashov Kazan State Medical University, Kazan, Tatarstan, Russia

    L. E. Nikitina, V. A. Startseva, I. A. Vakulenko & V. V. Plemenkov

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  1. L. E. Nikitina
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  2. V. A. Startseva
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  3. I. A. Vakulenko
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  4. V. V. Plemenkov
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Nikitina, L.E., Startseva, V.A., Vakulenko, I.A. et al. Synthesis of Polyfunctional Terpenoids from Monoterpenes and N-(2-Mercaptopropyonyl)glycine. Russian Journal of General Chemistry 72, 974–975 (2002). https://doi.org/10.1023/A:1020459013118

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  • DOI: https://doi.org/10.1023/A:1020459013118

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