Abstract
Hair samples of mildly mentally retarded (LR), moderately mentally retarded (MR), severely mentally retarded (SR) and normal children were collected and measured, using neutron activation analysis and X-ray fluorescence to determine the concentrations of Al, Sb, As, Ca, Cu, I, Fe, Pb, Mg, Mn, Hg, K, Sr, S, V and Zn. The groups of children were of ages between 5 and 13. Difference in the mean concentration of each element between groups was tested by Student"s t-test. No trend, either decreasing or increasing, has been established as the degree of severity increased from normal to SR children, except for the case of Cu. The present work may shed some light in the interpretation of findings on the effects of trace elements on neurobehavioral functions.
Similar content being viewed by others
References
O. J. DAVID, B. MCGANN, S. HOFFMAN, Lancet, 6 (1976) 1376.
H. L. NEEDLEMAN, C. GUNNOE, A. LEVITON, New England J. Med., 300 (1979) 689.
R. O. PIHL, McGill J. Educ., 14 (1979) 353.
R. FREEDMAN, L. OLSON, B. J. HOFFER, Environ. Health Perspect., 89 (1990) 27.
B. A. HAWK, S. R. SCHROEDER, G. ROBINSON, Amer. J. Mental Defic., 91 (1986) 178.
J. D. MITCHELL, B. W. EAST, I. A. HARRIS, J. Neurol. Neurosurg. Psychiatry, 49 (1986) 211.
M. MARLOWE, J. ERRERA, Amer. J. Mental Defic., 87 (1983) 477.
R. O. PIHL, M. PARKES, Science, 198 (1977) 204.
E. J. UNDERWOOD, Philos. Trans. R. Soc. Lond., B288 (1979) 5.
A. A. E. WIBOWO, B. BRUNEKREEF, E. LEBRET, Intern. Arch. Occup. Environ. Health, 46 (1980) 275.
P. GRANDJEAN, Human Toxicol., 3 (1984) 223.
N. LIMIC, V. VALKOVIC, Bull. Environ. Contam. Toxicol., 37 (1986) 925.
S. A. KATZ, Biol. Trace Elem. Research, 36 (1993) 1.
J. CHATTERJEE, D. KUNTALA, D. K. ARABINDA, Health Phys., 65 (1993) 351.
C. K. MAN, Y. H. ZHENG, P. K. MAK, J. Radioanal. Nucl. Chem., 212 (1996) 151.
S. A. KATZ, R. B. KATZ, J. Appl. Toxicol., 12 (1992) 79.
G. GARDNER-MEDWIN, Developmental Abnormalities of the Nervous System, Oxford Textbook of Medicine, Vol. 2, 2nd ed., D. J. WEATHERALL et al. (Eds), Oxford Medical Publications, 1988.
American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 3rd ed., American Psychiatric Association, Washington, DC, 1987.
L. I. ZHUK, A. A. KIST, Biol. Trace Element Res., 26 (1990) 307.
R. A. PASSWATER, E. M. CRANTON, Trace Elements, Hair Analysis and Nutrition, Keats Publishing Inc., New Canaan, CT, 1983.
H. T. DELVES, Copper and Zinc, in: Quantitative Trace Analysis of Biological Materials, H. A. MCKENZIE and L. E. SMYTHE (Eds), Elsevier Science Publishers, Amsterstam, 1988.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Man, C.K., Zheng, Y.H. Analysis of trace elements in scalp hair of mentally retarded children. Journal of Radioanalytical and Nuclear Chemistry 253, 375–377 (2002). https://doi.org/10.1023/A:1020405100202
Issue Date:
DOI: https://doi.org/10.1023/A:1020405100202