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Chromatographic Analysis of Isoniconitic Acid Hydrazide Derivatives

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Abstract

A highly sensitive and selective procedure was developed for determining specific impurities of isonicotinic acid hydrazide and vanillin in Metazid and Ftivazide preparations by thin-layer chromatography.

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REFERENCES

  1. Farmakopeinaya Stat'ya (Pharmacopoeia Item) 42-2468-96: Metazid: Coll. of Items, Pershin, G.N., Ed., Moscow: Medgiz, 1960.

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  2. Farmakopeinaya Stat'ya (Pharmacopoeia Item) 42-3266-96: Ftivazide: Coll. of Items, Pershin, G.N., Ed., Moscow: Medgiz, 1954.

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  3. Bolliger, H.R., Brenner, M., and Günshirt, H., Dünnschicht Chromatographie. Ein Laboratoriumshandbuch, Stahl, E., Ed., Berlin: Springer, 1962.

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Illarionova, E.A., Abramova, L.V. & Illarionov, A.I. Chromatographic Analysis of Isoniconitic Acid Hydrazide Derivatives. Russian Journal of Applied Chemistry 75, 768–770 (2002). https://doi.org/10.1023/A:1020358512326

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  • DOI: https://doi.org/10.1023/A:1020358512326

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