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Pine Resin and Biopin Ointment: Effects on Cell Composition and Histochemical Changes in Wounds

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Abstract

We studied the effects of Biopin ointment containing pine resin and used for the therapy of burns, wounds, and purulent and inflammatory diseases on the cell composition of wounds and histochemical changes in the granulation tissue during the therapy of extensive third-degree burns. The preparation stimulated the nonspecific immune response, normalized hemodynamics in damaged regions, and stimulated cell proliferation in the squamous epithelium.

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REFERENCES

  1. B. M. Datsenko, Theory and Practice of Local Therapy of Purulent Wounds (Problems of Drug Therapy) [in Russian], Kiev (1995).

  2. B. A. Paramonov and G. Sh. Mchedlidze, Therapy of Burns, Wounds, and Trophic Ulcers with Ointment Biopin [in Russian], St. Petersburg (2001).

  3. B. A. Paramonov, Ya. O. Porembskii, and V. G. Yablonskii, Burns: Manual for Physicians [in Russian], St. Petersburg (2000).

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Authors and Affiliations

  1. Institute of High-Purity Biological Preparations, Russia

    O. K. Khmel'nitskii, A. S. Simbirtsev, V. G. Konusova, G. Sh. Mchedlidze, E. Z. Fidarov, B. A. Paramonov & V. Yu. Chebotarev

  2. St. Petersburg-Technology, St. Petersburg

    O. K. Khmel'nitskii, A. S. Simbirtsev, V. G. Konusova, G. Sh. Mchedlidze, E. Z. Fidarov, B. A. Paramonov & V. Yu. Chebotarev

Authors
  1. O. K. Khmel'nitskii
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  2. A. S. Simbirtsev
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  3. V. G. Konusova
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  4. G. Sh. Mchedlidze
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  5. E. Z. Fidarov
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  6. B. A. Paramonov
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  7. V. Yu. Chebotarev
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Correspondence to V. Yu. Chebotarev.

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Khmel'nitskii, O.K., Simbirtsev, A.S., Konusova, V.G. et al. Pine Resin and Biopin Ointment: Effects on Cell Composition and Histochemical Changes in Wounds. Bulletin of Experimental Biology and Medicine 133, 583–585 (2002). https://doi.org/10.1023/A:1020290010605

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  • DOI: https://doi.org/10.1023/A:1020290010605

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