Abstract
The single crystal structures of 4-(5-(1,3-benzodioxole)-2,6-dimethyl-1,4-dihydropyridine-3,5-bis(methoxycarbonyl) (I), 4-(3-pyridyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-bis (methoxycarbonyl) (II), 4-(3(1-methyl-1H-indole))-2,6-dimethyl-1,4-dihydropyridine-3, 5-bis(methoxycarbonyl) (III), and 4-cyclopentadienyl-2,6-dimethyl-1,4-dihydropyridine-3,5-bis(methoxycarbonyl) (IV) suggest that these members of a calcium beta blocking family may dock with their receptor sites from the A ring end of the molecule.
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Caignan, G.A., Holt, E.M. New 1,4-dihydropyridine derivatives with hetero and saturated B rings. Journal of Chemical Crystallography 32, 315–323 (2002). https://doi.org/10.1023/A:1020209608962
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DOI: https://doi.org/10.1023/A:1020209608962