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Effect of Palmitic and Lauric Acids on the Phospholipid Bilayer Membrane Conductivity

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Bioscience Reports

Abstract

Palmitic acid increased the conductivity of BLM from mitochondrial phospholipids when they were dissolved in a mixture of decane and chlorodecane, and was ineffective when phospholipids were dissolved in decane. Lauric acid produced an increase in the membrane conductivity independently of the phospholipid type in the membrane-forming solutions (mitochondrial phospholipids, asolectin, lecithin with cholesterol) and their solvents (decane or decane with chlorodecane). The results show that discrepancies between published data concerning fatty acid effects on the BLM conductivity may be explained by differences in phospholipids, their solvents and fatty acid used.

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Authors and Affiliations

  1. Institute of Information Transmission Problems, Russian Academy of Sciences, Ermolova str., 19, Moscow, 101447, Russia

    L. M. Tsofina

  2. A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, 119899, Russia

    E. N. Mokhova

Authors
  1. L. M. Tsofina
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  2. E. N. Mokhova
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Tsofina, L.M., Mokhova, E.N. Effect of Palmitic and Lauric Acids on the Phospholipid Bilayer Membrane Conductivity. Biosci Rep 18, 91–95 (1998). https://doi.org/10.1023/A:1020136327022

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