Skip to main content
SpringerLink
Log in

Pine Resin and Biopin Ointment: Effects on Repair Processes in Tissues

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effects of Biopin (ointment containing pine resin) used in the treatment of burns, wounds, and pyoinflammatory processes on cell composition of the wound surface (smears) and granulation tissue were studied on rats. In vitro antibacterial activity of the drug was also evaluated. At the early stage of inflammation Biopin modulated the nonspecific and inhibited specific cell immune response, normalized hemodynamics in the inflammation focus, activated synthetic processes in the wound, and was effective towards anaerobes and bacilli.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. B. M. Datsenko, Theory and Practical Local Treatment of Purulent Wounds (Problems of Drug Therapy) [in Russian], Kiev (1995).

  2. B. A. Paramonov and G. Sh. Mchelidze, Therapy of Burns, Wounds, and Trophic Ulcers Using Biopin Ointment [in Russian], St. Petersburg (2001).

  3. A. Clark, Arch. Dermatol., 124, 201–206 (1988).

    Google Scholar 

  4. F. Grinnel, T. Ken-Ichi, and A. Takashima, J. Cell. Sci., Suppl. 8, 199–209 (1987).

    Google Scholar 

  5. C. Kane, P. Hebda, and J. Mansbridge, J. Cell Physiol., 148, 157–173 (1991).

    Google Scholar 

  6. Y.-C. Lin and F. Grinnel, J. Cell Biol., 122, 663–672 (1993).

    Google Scholar 

  7. E. Mackie, W. Halfer, and D. Livenari, Ibid., 107, 2757–2767 (1988).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. State Institute of Extra Pure Biopreparations, Russia

    A. S. Simbirtsev, V. G. Konusova, G. Sh. Mchelidze, E. Z. Fidarov, B. A. Paramonov & V. Yu. Chebotarev

  2. SPb-Tekhnologiya, St. Petersburg

    A. S. Simbirtsev, V. G. Konusova, G. Sh. Mchelidze, E. Z. Fidarov, B. A. Paramonov & V. Yu. Chebotarev

Authors
  1. A. S. Simbirtsev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. G. Konusova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. Sh. Mchelidze
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. E. Z. Fidarov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. B. A. Paramonov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. V. Yu. Chebotarev
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. Yu. Chebotarev.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Simbirtsev, A.S., Konusova, V.G., Mchelidze, G.S. et al. Pine Resin and Biopin Ointment: Effects on Repair Processes in Tissues. Bulletin of Experimental Biology and Medicine 133, 457–460 (2002). https://doi.org/10.1023/A:1019805603373

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1019805603373

Search

Navigation