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Synthesis of substituted thiophenes based on fluorine-containing β-functionalized vinyl sulfides

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Abstract

Derivatives of fluorine-containing 3-(methoxycarbonylmethylthio)acrylic acids readily undergo base-catalyzed cyclization to form 3-hydroxy- and 3-aminothiophenes.

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References

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Kovregin, A.N., Sizov, A.Y. & Ermolov, A.F. Synthesis of substituted thiophenes based on fluorine-containing β-functionalized vinyl sulfides. Russian Chemical Bulletin 51, 1028–1030 (2002). https://doi.org/10.1023/A:1019621904338

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  • DOI: https://doi.org/10.1023/A:1019621904338

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