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Intravesical treatment of severe bacillus Calmette-Guerin cystitis

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Abstract

Objective: Intravesical instillation of bacillus Calmette-Guerin (BCG) is an established treatment of carcinoma in situ and recurrent superficialbladder tumours. The inflammatory reaction due to BCG provokes cystitisof short duration as a frequent side effect. When the symptomatology issevere and long-lasting, different systemic treatments have beenadministered with varying degrees of efficacy.Material and methods: We have studied the treatment of severe BCG cystitiswith a anaesthetic anti-inflammatory solution administered by intravesicalinstillations to 16 patients.Results: Good results were obtained in 94% of the cases, with immediateclinical improvement in terms of pain and urinary symptoms, and with noside effects.Conclusions: This treatment is inexpensive and easy to administer. Weconsider that it offers a useful option to solve an infrequent but veryannoying problem for the patients.

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Authors and Affiliations

  1. Department of Urology and Pharmacy, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, Spain

    J. Palou, L. Rodríguez-Villamil, A. Andreu-Crespo, J. Salvador-Bayarri & J. Vicente-Rodríguez

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  1. J. Palou
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  2. L. Rodríguez-Villamil
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  3. A. Andreu-Crespo
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  4. J. Salvador-Bayarri
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  5. J. Vicente-Rodríguez
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Palou, J., Rodríguez-Villamil, L., Andreu-Crespo, A. et al. Intravesical treatment of severe bacillus Calmette-Guerin cystitis. Int Urol Nephrol 33, 485–489 (2001). https://doi.org/10.1023/A:1019507104741

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