Polyfunctional Biologically Active Polyvinyl Alcohol Film Materials

Abstract

Incorporation of sodium alginate in the spinning solution in the amount of 2% decreases the rate of inactivation of protease C immobilized in the structure of a polyvinyl alcohol film material by two times and decreases the amount of desorbed polyhexamethyleneguanidine hydrochloride by ten times, giving the film self-disinfecting properties. Addition of sodium tetraborate in the spinning solution increases the PHMG desorption rate by 1.5-4.5 times. When PHMG with a molecular weight of 10,000 is used, total desorption of the antimicrobial from the film materials can be obtained. When modifying additives are used (sodium alginate and tetraborate), the optimum pH of the action of the protease immobilized in the structure of the film is shifted to the region of lower values (pH 8), which increases the efficiency of the action of the enzyme-containing film material in the conditions of use.