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Modelling a biosensor based on the heterogeneous microreactor

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Abstract

Modelling of the amperometric biosensors based on carbon paste electrodes encrusted with a single heterogeneous microreactor is analyzed. The microreactor was constructed from CPC‐silica carrier and was loaded with glucose oxidase. The model is based on non‐stationary diffusion–reaction equations containing a non‐linear term related to the enzymatic reaction. A homogenization process having an effective algorithm for the digital modelling of the operation of the microreactor is proposed. The influence of the size, geometrical form, and the position of a microreactor on the operation of biosensors are investigated.

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Authors and Affiliations

  1. Faculty of Mathematics and Informatics, Vilnius University, Naugarduko 24, 2600, Vilnius, Lithuania

    R. Baronas & F. Ivanauskas

  2. Institute of Mathematics and Informatics, Akademijos 4, 2600, Vilnius, Lithuania

    F. Ivanauskas

  3. Laboratory of Enzyme Chemistry, Institute of Biochemistry, Mokslininku 12, 2600, Vilnius, Lithuania

    J. Kulys

Authors
  1. R. Baronas
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  2. F. Ivanauskas
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  3. J. Kulys
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Baronas, R., Ivanauskas, F. & Kulys, J. Modelling a biosensor based on the heterogeneous microreactor. Journal of Mathematical Chemistry 25, 245–252 (1999). https://doi.org/10.1023/A:1019192618843

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  • DOI: https://doi.org/10.1023/A:1019192618843

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