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Alkylation of pyrazoles with alcohols over zeolites

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Abstract

HY zeolite is a highly active catalyst for the vapor-phase N-alkylation of pyrazoles with alcohols. For example, the reactions of pyrazole and 4-methylpyrazole with methanol over HY afford N-methylpyrazole and 1,4-dimethylpyrazole, respectively, in a 100% yield at 573 K.

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Ono, Y., Izawa, Y. & Fu, ZH. Alkylation of pyrazoles with alcohols over zeolites. Catalysis Letters 47, 251–253 (1997). https://doi.org/10.1023/A:1019065323538

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  • DOI: https://doi.org/10.1023/A:1019065323538

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