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Entrapping Efficiency of an Oil-in-Water Emulsion Containing Isocarbacyclin Methyl Ester (TEI-9090) in Dog and Human Sera

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REFERENCES

  1. M. Shibasaki, Y. Torisawa and S. Ikegami. Synthesis of 9(0)-methano-Δ6(9a)-PGI1: the highly potent carbon analog of prostacyclin. Tetrahedron Lett. 24:3493–3496 (1983).

    Google Scholar 

  2. Y. Mizushima, R. Igarashi, K. Hoshi, A. K. Sim, M. E. Cleland, H. Hayashi and J. Goto. Marked enhancement in antithrombotic activity of isocarbacyclin following its incorporation into lipid microspheres. Prostaglandins 33:161–168 (1987).

    Google Scholar 

  3. T. Minagawa, Y. Kohno, T. Suwa and A. Tsuji. Entrapping efficiency and drug release profile of an oil-in-water (o/w) emulsion formulation using a polydimethylsiloxane-coated glass bead assay. Pharm. Res. 11:503–507 (1994).

    Google Scholar 

  4. T. Minagawa, Y. Kohno, T. Suwa and A. Tsuji. Determination of protein binding of a highly lipophilic drug using a polydimethylsiloxane-coated glass beads assay. J. Pharm. Pharmacol. in press (1994).

  5. R. Takeshita and H. Yoshida. Studies on anion active surfactants. I. Determination of anion active surfactants in natural and waste waters using cleanup by Amberlite XAD 2 column chromatography. Jpn. J. Toxicol. Environ. Health 11:209–215 (1975).

    Google Scholar 

  6. M. L. Corrin and W. D. Harkins. The effect of salts on the critical concentration for the formulation of micelles in colloidal electrolytes. J. Am. Chem. Soc. 69:683–688 (1945).

    Google Scholar 

  7. J. Reynolds, S. Herbert and J. Steinhardt. The binding of some long-chain fatty acid anions and alcohols by bovine serum albumin. Biochemistry 7:1357–1361 (1968).

    Google Scholar 

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Minagawa, T., Kohno, Y., Suwa, T. et al. Entrapping Efficiency of an Oil-in-Water Emulsion Containing Isocarbacyclin Methyl Ester (TEI-9090) in Dog and Human Sera. Pharm Res 11, 1677–1679 (1994). https://doi.org/10.1023/A:1018938627408

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  • DOI: https://doi.org/10.1023/A:1018938627408

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