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Case Report: Gastrointestinal Amyloidosis Secondary to Hypersensitivity Vasculitis Presenting with Intestinal Pseudoobstruction

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Abstract

Hypersensitivity vasculitis is characterized byinflammation and necrosis of small blood vesselssecondary to allergic or hypersensitivity mechanisms (1,2). Gastrointestinal involvement with edema and bleeding also has been reported (3-5).Long-standing inflammation, such as rheumatic disease,infectious disease, inflammatory bowel disease, familialMediterranean fever, and malignancy, may lead tosystemic amyloidosis (6). Gastrointestinal involvementmay induce anorexia, nausea and vomiting, diarrhea,constipation, bleeding, malabsorption, andpseudoobstruction (6, 10-12). In this report we discussa patient with hypersensitivity vasculitis with severeintestinal bleeding who developed systemic amyloidosiswith intestinal pseudoobstruction 29 months after onset.Secondary amyloidosis due to hypersensitivity vasculitis has not been previously reported,and the causal relationship is discussed in thisreport.

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Authors
  1. Katsushi Hiramatsu
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  2. Shuichi Kaneko
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  3. Yukihiro Shirota
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  4. Mitsuru Matsuda
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  5. Kyosuke Kaji
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  6. Yosio Kitano
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  7. Naoki Ikeda
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  8. Shuichi Terasaki
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  9. Hiroshi Kawai
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  10. Atsushi Shimoda
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  11. Hitoshi Yokoyama
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  12. Eiki Matsushita
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  13. Takeshi Urabe
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  14. Kenichi Kobayashi
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Hiramatsu, K., Kaneko, S., Shirota, Y. et al. Case Report: Gastrointestinal Amyloidosis Secondary to Hypersensitivity Vasculitis Presenting with Intestinal Pseudoobstruction. Dig Dis Sci 43, 1824–1830 (1998). https://doi.org/10.1023/A:1018856324810

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  • DOI: https://doi.org/10.1023/A:1018856324810

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