Skip to main content
SpringerLink
Log in

The Anopheles albimanus white gene: molecular characterization of the gene and a spontaneous white gene mutation

  • Published:
Genetica Aims and scope Submit manuscript

Abstract

We have cloned and characterized the white gene of Anopheles albimanus. Comparison of the deduced amino acid sequence of this white gene with its homologs from six species of Diptera show that the An. albimanus gene is most similar to the white gene of An. gambiae (92% identity). A spontaneous white-eyed mutant An. albimanus was caused by an approximately 10 kb insertion into a CT dinucleotide repeat region of intron 2 of the white locus. The flanks of this insertion are long (at least 400 bp), nearly perfect inverted terminal repeat sequences. This cloned white gene should be useful as a marker for germ line transformation of An. albimanus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Entomology Branch, Mailstop F22, Division of Parasitic Diseases, Centers for Disease Control and Prevention, Chamblee, GA, 30341, USA

    Zhaoxi Ke, Mark Q. Benedict, Anthony J. Cornel, Nora J. Besansky & Frank H. Collins

  2. Department of Biology, Emory University, Atlanta, GA, 30322, USA

    Zhaoxi Ke, Nora J. Besansky & Frank H. Collins

  3. Department of Biological Sciences, Galvin Life Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA

    Zhaoxi Ke

  4. Mosquito Control Research Laboratories, Kearney Agricultural Experimental Field Station, University of California, 9240 South Riverbend Ave, Parlier, CA, 93648, USA

    Anthony J. Cornel

Authors
  1. Zhaoxi Ke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mark Q. Benedict
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Anthony J. Cornel
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Nora J. Besansky
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Frank H. Collins
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ke, Z., Benedict, M.Q., Cornel, A.J. et al. The Anopheles albimanus white gene: molecular characterization of the gene and a spontaneous white gene mutation. Genetica 101, 87–96 (1997). https://doi.org/10.1023/A:1018376525897

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1018376525897

Search

Navigation