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Comparison of air-lift and stirred tank reactors for itaconic acid production by Aspergillus terreus

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Abstract

In a 2-l stirred tank reactor (STR), maximum production rate ofitaconic acid was 0.48g/l.h , for an agitation rate of 400 rpm andan aeration rate of 0.5 vvm. In an air-lift reactor (ALR) themaximum production rate was 0.64 g/l.h at an O supply rate of0.41 l O /l. min. Power input per unit volume which gave themaximum production rates for STR and ALR were 1180 and 542 W/m 3,respectively. If O -enriched air was used in place of air for ALR,the corre-sponding power input per unit volume was decreased to 34W/m 3 . ALR requires less power input per unit volume in comparisonwith that of STR whether therefore air or O -enriched air is used.ALR would be a suitable bioreactor for a large production of itaconicacid.

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Authors and Affiliations

  1. Central Laboratory, Bio-Chiba Co. Ltd., Tokyo

    Kazutoyo Yahiro

  2. Department of Applied Biological Chemistry, Faculty of Agriculture, University of Shizuoka, 836 Ohya, Shizuoka, 422, Japan

    Tetsusi Takahama, Yongsoo Park & Mitsuyasu Okabe

  3. Department of Fermentation Technology, Tianjin Instituteof Light Industry, Tianjin, China

    Shi-ru Jai

Authors
  1. Kazutoyo Yahiro
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  2. Tetsusi Takahama
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  3. Shi-ru Jai
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  4. Yongsoo Park
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  5. Mitsuyasu Okabe
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Yahiro, K., Takahama, T., Jai, Sr. et al. Comparison of air-lift and stirred tank reactors for itaconic acid production by Aspergillus terreus. Biotechnology Letters 19, 619–621 (1997). https://doi.org/10.1023/A:1018374428391

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  • DOI: https://doi.org/10.1023/A:1018374428391

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