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Cryptocaryon irritans Brown 1951, the cause of ‘white spot disease’ in marine fish: an update

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Aquarium Sciences and Conservation

Abstract

Cryptocaryon irritans Brown 1951, a holotrichous ciliate parasite of marine fishes, causes ‘marine white spot disease’. In aquaria, C. irritans can cause acute damage and heavy mortalities to marine teleosts. Although first described 60 years ago, only within the last decade has detailed information emerged concerning its life cycle, transmission and pathogenesis. An update of our knowledge of this important aquarium fish parasite is presented here.

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REFERENCES

  • Andrews, C., Exell, A. and Carrington, N. (1988) The Interpet Manual of Fish Health. London: Salamander Books Ltd.

    Google Scholar 

  • Ayroud, M. (1982) Cryptocaryon: an annotated review. Drum and Croaker 20, 14–19.

    Google Scholar 

  • Blasiola, G.C. (1976) A review of `white spot', Cryptocaryon irritans. Marine Aquarist 7, 5–14.

    Google Scholar 

  • Brown, E.M. (1951) Cryptocaryon irritans gen. et sp. n. Agenda and Abstracts of the Scientific Meetings of the Zoological Society of London, 1950, 1–2.

    Google Scholar 

  • Brown, E.M. (1963) Studies on Cryptocaryon irritans Brown. In Proceedings of the First International Congress on Protozoology. Prague: Czechoslovak Academy of Sciences, pp. 284–287.

    Google Scholar 

  • Bunkley-Williams, L. and Williams, E.H., Jr (1994) Diseases caused by Trichodina spheroidesi and Cryptocaryon irritans (Ciliophora) in wild coral reef fishes. Journal of Aquatic Animal Health 6, 360–361.

    Article  Google Scholar 

  • Burgess, P.J. (1992) Cryptocaryon irritans Brown, 1951 (Ciliophora): transmission and immune response in the mullet Chelon labrosus (Risso, 1826). PhD thesis, University of Plymouth.

  • Burgess, P.J. and Matthews, R.A. (1994a) A standardized method for the in vivo maintenance of Cryptocaryon irritans (Ciliophora) using the grey mullet Chelon labrosus as an experimental host. Journal of Parasitology 80, 288–292.

    PubMed  Google Scholar 

  • Burgess, P.J. and Matthews, R.A. (1994b) Cryptocaryon irritans (Ciliophora): photoperiod and transmission in marine fish. Journal of the Marine Biological Association of the United Kingdom 74, 445–453.

    Google Scholar 

  • Burgess, P.J. and Matthews, R.A. (1995a) Fish host range of seven isolates of Cryptocaryon irritans (Ciliophora). Journal of Fish Biology 46, 727–729.

    Google Scholar 

  • Burgess, P.J. and Matthews, R.A. (1995b) Cryptocaryon irritans (Ciliophora): acquired protective immunity in the thick-lipped mullet, Chelon labrosus. Fish and Shellfish Immunology 5, 459–468.

    Article  Google Scholar 

  • Canella, M.F. (1972) Ce qu'on ne connaît pas sur un holotriche ectoparasite des poissons marins, découvert par le Dr. Sikama et appelé Cryptocaryon irritans par Miss Brown. Contributions à la connaissance des Ciliés, VII. Annali dell'Università di Ferrara, Italy, Nuova Serie, Sez. III, Biologia Animale III(9), 107–132.

    Google Scholar 

  • Canella, M.F. and Rocchi-Canella, I. (1976) Biologie des Ophryoglenina (ciliés hymenostomes histophages). Annali dell'Università di Ferrara, III(3) (Suppl. 2), 1–510.

    Google Scholar 

  • Cassidy, E.J. (1995) Latest scientific discoveries involving nitrifying bacteria. Freshwater and Marine Aquarium 18(3), 140–154.

    Google Scholar 

  • Cheong, L. (1990) Status of knowledge on farming of seabass (Lates calcarifer) in South East Asia. Advances in Tropical Aquaculture, Tahiti, February 20-March 4, 1989. AQUACOP, IFREMER, Actes de Colloque 9, 421–428.

    Google Scholar 

  • Cheung, P.J., Nigrelli, R.F. and Ruggieri, G.D. (1979) Studies on cryptocaryoniasis in marine fish: effect of temperature and salinity on the reproductive cycle of Cryptocaryon irritans Brown, 1951. Journal of Fish Diseases 2, 93–97.

    Google Scholar 

  • Cheung, P.J., Nigrelli, R.F. and Ruggieri, G.D. (1980) Studies on the morphology of Uronema marinum Dujardin (Ciliatea: Uronematidae) with a description of the histopathology of the infection in marine fishes. Journal of Fish Diseases 3, 295–303.

    Google Scholar 

  • Colorni, A. (1985) Aspects of the biology of Cryptocaryon irritans, and hyposalinity as a control measure in cultured gilt-head sea bream Sparus aurata. Diseases of Aquatic Organisms 1, 19–22.

    Google Scholar 

  • Colorni, A. (1987) Biology of Cryptocaryon irritans and strategies for its control. Aquaculture 67, 236–237.

    Article  Google Scholar 

  • Colorni, A. (1992) Biology, pathogenesis and ultrastructure of the holotrich ciliate Cryptocaryon irritans Brown 1951, a parasite of marine fish. PhD thesis, Hebrew University of Jerusalem.

  • Colorni, A. and Diamant, A. (1993) Ultrastructural features of Cryptocaryon irritans, a ciliate parasite of marine fish. European Journal of Protistology 29(12), 425–434.

    Google Scholar 

  • de Graaf, F. (1962) A new parasite causing epidemic infection in captive coralfishes. Bulletin de L'Institut Oceanographique, Monaco. Numero special 1A: 1er Congrès International d'Aquariologie, Monaco, 1960. Communications, Volume A, 93–96.

    Google Scholar 

  • de Graaf, F. (1973) Marine Aquarium Guide. London: Pet Library.

    Google Scholar 

  • Diamant, A., Issar, G., Colorni, A. and Paperna, I. (1991) A pathogenic Cryptocaryon-like ciliate from the Mediterranean Sea. Bulletin of the European Association of Fish Pathologists 11(3), 122–124.

    Google Scholar 

  • Dickerson, H.W. and Dawe, D.L. (1995) Ichthyophthirius multifiliis and Cryptocaryon irritans (Phylum Ciliophora). In Woo, P.T.K., ed., Fish Diseases and Disorders, Vol. 1, Protozoan and Metazoan Infections. Cambridge: CAB International, pp. 181–227.

    Google Scholar 

  • Diggles, B.K. and Adlard, R.D. (1995) Taxonomic affinities of Cryptocaryon irritans and Ichthyophthirius multifiliis inferred from ribosomal RNA sequence data. Diseases of Aquatic Organisms 22(1), 39–43.

    Google Scholar 

  • Diggles, B.K. and Adlard, R.D. (1997) Intraspecific variation in Cryptocaryon irritans. Journal of Eukaryotic Microbiology 44(1), 25–32.

    PubMed  Google Scholar 

  • Diggles, B.K. and Lester, J.G. (1996a) Influence of temperature and host species on the development of Cryptocaryon irritans. Journal of Parasitology 82(1), 45–51.

    Article  PubMed  Google Scholar 

  • Diggles, B.K. and Lester, J.G. (1996b) Variation in the development of two isolates of Cryptocaryon irritans. Journal of Parasitology 82(3), 384–388.

    PubMed  Google Scholar 

  • Diggles, B.K. and Lester, J.G. (1996c) Infections of Cryptocaryon irritans on wild fish from southeast Queensland, Australia. Diseases of Aquatic Organisms 25(3), 159–167.

    Google Scholar 

  • Dragesco, A., Dragesco, J., Coste, F., Gasc, C., Romestand, B., Raymond, J.-C. and Bouix, G. (1995) Philasterides dicentrarchi, n. sp., (Ciliophora, Scuticociliatida), a histophagous opportunistic parasite of Dicentrarchus labrax (Linnaeus, 1758), a reared marine fish. European Journal of Protistology 31, 327–340.

    Google Scholar 

  • Gallet de Saint Aurin, D., Raymond, J.C. and Vianas, V. (1990) Marine finfish pathology: specific problems and research in the French West Indies. Advances in Tropical Aquaculture, Tahiti, February 20-March 4, 1989. AQUACOP, IFREMER, Actes de Colloque 9, 143–160.

    Google Scholar 

  • Giavenni, R. (1982) Considerazioni sulle più diffuse forme morbose riscontrabili a carico dei pesci ornamentali. II-Pesci Tropicali Marini. Rivista Italiana di Piscicoltura e Ittiopatologia 1, 30–36.

    Google Scholar 

  • Gratzek, J.B., Gilbert, J.P., Lohr, A.L., Shotts, E.B. and Brown, J. (1983) Ultraviolet light control of Ichthyophthirius multifiliis in a closed fish culture recirculation system. Journal of Fish Diseases 6, 145–153.

    Google Scholar 

  • Herwig, N. (1978) Notes on the treatment of Cryptocaryon. Drum and Croaker 18(1), 6–12.

    Google Scholar 

  • Herwig, N. (1979) Handbook of Drugs and Chemicals Used in the Treatment of Fish Diseases. Illinois: Charles C. Thomas Publisher.

    Google Scholar 

  • Hignette, M. (1981) Utilization de sels métalliques comme traitement antiparasitaire en aquariologie marine. Vie Marine 3, 133–138.

    Google Scholar 

  • Hine, P.M. (1982) Potential disease in snapper farming. In Prospects for Snapper Farming and Reseeding in New Zealand. (Compilers: P.J. Smith and J.L. Taylor). Fisheries Research Division Occasional Publication N. 37, pp. 21–23.

    Google Scholar 

  • Hoffman, G.L. (1974) Disinfection of contaminated water by ultraviolet irradiation, with emphasis on whirling disease (Myxosoma cerebralis): and its effect on fish. Transactions of the American Fisheries Society 103, 541–550.

    Article  Google Scholar 

  • Hua, D.-K., Cai, M.-L. and Zhang, Z.-Y. (1994) Studies on the grouper's syndrome I. Etiology and histopathology. In Chou, L.M., Munro, A.D., Lam, T.J., Chen, T.W., Cheong, L.K.K., Ding, J.K., Hooi, K.K., Khoo, H.W., Phang, V.P.E., Shim, K.F. and Tan, C.H., eds, The Third Asian Fisheries Forum. Manila: Asian Fisheries Society, pp 353–356.

    Google Scholar 

  • Huff, J.A. and Burns, C.D. (1981) Hypersaline and chemical control of Cryptocaryon irritans in red snapper, Lutjanus campechanus, monoculture. Aquaculture 22, 181–184.

    Article  Google Scholar 

  • Kaige, N. and Miyazaki, T. (1985) A histopathological study of white spot disease in Japanese flounder. Fish Pathology 20(1), 61–64.

    Google Scholar 

  • Keith, R.E. (1981) Loss of therapeutic copper in closed marine systems. Aquaculture 24, 355–362.

    Article  Google Scholar 

  • Kerbert, C. (1884) Chromatophagus parasiticus n. g. et n. sp. Ein Beitrag zur Parasitenlehre. Nederlandsch Tijdschrift voor d. Dierkunde, Amsterdam 5, 44–58.

    Google Scholar 

  • Kingsford, E. (1975) Treatment of Exotic Marine Fish Diseases. Florida: Palmetto Publishing Company.

    Google Scholar 

  • Laird, M. (1956) Aspects of fish parasitology. In Proceedings of the Second Joint Symposium of the Science Society of Malaya and Malayan Mathematical Society, pp. 46–54.

  • Leong, T.-S. and Wong, S.-Y. (1988) A comparative study of the parasite fauna of wild and cultured grouper (Epinephelus malabaricus Bloch et Schneider) in Malaysia. Aquaculture 68, 203–207.

    Article  Google Scholar 

  • Lom, J. (1984) Diseases caused by protistans. In Kinne, O., ed., Diseases of Marine Animals. Hamburg: Biologische Anstalt Helgoland, 114–168.

    Google Scholar 

  • Lom, J. and Dyková, I. (1992) Protozoan Parasites of Fishes. Amsterdam: Elsevier.

    Google Scholar 

  • Lowe-McConnell, R.H. (1987) Ecological Studies in Tropical Fish Communities. Cambridge, UK: Cambridge University Press.

    Google Scholar 

  • Matthews, R.A. and Burgess, P.J. (1995) Cryptocaryon irritans (Ciliophora): primary infection in thick-lipped mullet, Chelon labrosus (Risso). Journal of Fish Diseases 18, 329–335.

    Google Scholar 

  • Matthews, B.F., Matthews, R.A. and Burgess, P.J. (1993) Cryptocaryon irritans Brown, 1951 (Ichthyophthiriidae): the ultrastructure of the somatic cortex throughout the life cycle. Journal of Fish Diseases 16, 339–349.

    Google Scholar 

  • Moe, M. (1982) The Marine Aquarium Handbook. Florida: Green Turtle Publications.

    Google Scholar 

  • Nie, D. and Lee, L.S. (1960) Studies on the morphology and life cycle of Ichthyophthirius multifiliis and its control, with a description of a new species. Acta Hydrobiologica Sinica 2, 197–255.

    Google Scholar 

  • Nigrelli, R.F. and Ruggieri, G.D. (1966) Enzootics in the New York Aquarium caused by Cryptocaryon irritans Brown, 1951 (=Ichthyophthirius marinus Sikama, 1961), a histophagous ciliate in the skin, eyes and gills of marine fishes. Zoologica 51(9), 97–102.

    Google Scholar 

  • Pill-Soon, S. and Walker, E.B. (1981) Molecular aspects of photoreceptors in protozoa and other microorganisms. In Levandowsky, M. and Hunter, S.H., eds, Biochemistry and Physiology of Protozoa, 2nd edn. London: Academic Press, pp. 199–233.

    Google Scholar 

  • Randall, J.E. (1968) Caribbean Reef Fishes. New York: TFH publications.

    Google Scholar 

  • Rasheed, V.M. (1989) Diseases of cultured brown-spotted grouper Epinephelus tauvina and silvery black porgy Acanthopagrus cuvieri in Kuwait. Journal of Aquatic Animal Health 1, 102–107.

    Article  Google Scholar 

  • Sikama, Y. (1937) Preliminary report on the white-spot disease in marine fishes. Suisan-Gakukai-Ho 7, 149–160.

    Google Scholar 

  • Sikama, Y. (1938) Ueber die Weisspünktchenkrankheit bei Seefischen. Journal of the Shanghai Science Institute, 4, 113–128.

    Google Scholar 

  • Sikama, Y. (1960) Contribution to the biological study of the diseases and parasites of fish in Japan. No. 2. White spot disease in marine fish and some similar disease. Bulletin of Marine Sciences 2, 189–200.

    Google Scholar 

  • Sikama, Y. (1961) On a new species of Ichthyophthirius found in marine fishes. Science Report of the Yokosuka City Museum 6, 66–70.

    Google Scholar 

  • Sikama, Y. (1962) Study on white spot disease in marine fish. Agriculture and Horticulture (Tokyo) 10(1), 29–90.

    Google Scholar 

  • Spotte, S. (1979) Seawater Aquariums: The Captive Environment. New York: John Wiley & Sons.

    Google Scholar 

  • Starck, W.A., II and Davis, W.P. (1966) Night habits of fishes of Alligator Reef, Florida. Ichthyologica 38, 313–356.

    Google Scholar 

  • Tareen, I.U. (1980) Heavy infection of cultured fish by Cryptocaryon irritans Brown 1951 (Protozoa-Ciliata). EMS Quarterly Newsletter 15, 83–86.

    Google Scholar 

  • Tookwinas, S. (1990a) Larviculture of seabass (Lates calcarifer) and grouper (Epinephelus malabaricus) in Thailand. Advances in Tropical Aquaculture, Tahiti, February 20-March 4, 1989. AQUACOP, IFREMER, Actes de Colloque 9, 645–659.

    Google Scholar 

  • Tookwinas, S. (1990b) Review of grow-out techniques under tropical conditions: experience in Thailand on seabass (Lates calcarifer) and grouper (Epinephelus malabaricus). Advances in Tropical Aquaculture, Tahiti, February 20-March 4, 1989. AQUACOP, IFREMER, Actes de Colloque 9, 737–750.

    Google Scholar 

  • Untergasser, D. (1989) Handbook of Fish Diseases. New Jersey: TFH publications.

    Google Scholar 

  • Van Duijn, C. (1973) Diseases of Fishes. London: Iliffe Books.

    Google Scholar 

  • Wilkie, D.W. and Gordin, H. (1969) Outbreak of cryptocaryoniasis in marine aquaria at Scripps Institution of Oceanography. California Fish and Game 55(3), 227–236.

    Google Scholar 

  • Xu, R., Jiang, J. and Cheng, B. (1992) Light microscopy observation on the life cycle of Cryptocaryon irritans. Marine Sciences 3, 42–44.

    Google Scholar 

  • Yoshinaga, T. and Dickerson, H.W. (1994) Laboratory propagation of Cryptocaryon irritans on a saltwater-adapted Poecilia hybrid, the Black Molly. Journal of Aquatic Animal Health 6, 197–201.

    Article  Google Scholar 

  • Yoshinaga, T., Nakane, M. and Hirose, H. (1997) Induction of apoptosis (suicide of cell) in host cells by Cryptocaryon irritans. In International Symposium on Diseases in Marine Aquaculture. Japanese Society of Fish Pathology 3–6 October 1997, Hiroshima, Japan.

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Colorni, A., Burgess, P. Cryptocaryon irritans Brown 1951, the cause of ‘white spot disease’ in marine fish: an update. Aquarium Sciences and Conservation 1, 217–238 (1997). https://doi.org/10.1023/A:1018360323287

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