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Solid-Phase Luminescence Determination of Ciprofloxacin and Norfloxacin in Biological Fluids

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Abstract

A simple, rapid, and sensitive luminescence test method for the determination of ciprofloxacin (CIP) and norfloxacin (NOR) has been described. The method is based on the intramolecular energy transfer from organic acid to terbium (Tb3+) ion. Luminescence of terbium (III) complex with CIP (NOR), sorbed on the zeolite has been studied. Under optimized conditions the detection limit is 1 μg/mL in urine and human plasma.

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Authors and Affiliations

  1. Odessa's State Academy of Food Technologies, 112, Kanatnaya St., Odessa, Ukraine

    Svetlana Beltyukova

  2. A. V. Bogatsky Physico-chemical Institute, National Academy of Sciences of Ukraine, 86, Lustdorfskaya doroga, Odessa, 65080, Ukraine

    Olga Teslyuk, Alla Egorova & Elena Tselik

Authors
  1. Svetlana Beltyukova
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  2. Olga Teslyuk
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  3. Alla Egorova
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  4. Elena Tselik
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Corresponding author

Correspondence to Alla Egorova.

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Beltyukova, S., Teslyuk, O., Egorova, A. et al. Solid-Phase Luminescence Determination of Ciprofloxacin and Norfloxacin in Biological Fluids. Journal of Fluorescence 12, 269–272 (2002). https://doi.org/10.1023/A:1016833422299

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  • DOI: https://doi.org/10.1023/A:1016833422299

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