Abstract
Polymorphism at the dopamine transporter gene (DAT1) in populations of the Volga–Ural region was examined by means of polymerase chain reaction. Statistically significant differences in the dopamine transporter gene allele and genotype frequency distribution were revealed both between the populations belonging to one ethnic group and between the populations from different linguistic families.
Similar content being viewed by others
REFERENCES
Vandenberg, D.J., Persico, A.M., Hawkins, A.L., et al., Human Dopamine Transporter Gene (DAT1) Maps to Chromosome 5p15.3 and Displays a VNTR, Genomics, 1992, vol. 14, pp. 1104-1106.
Persico, A.M., Bird, G., Gabbay, F.N., and Uhl, G.R., D2 Dopamine Receptor Gene TaqI A1 and B1 Restriction Fragment Length Polymorphisms: Enhanced Frequencies in Psychostimulant-Preffering Polysubstance Abusers, Biol. Psychiatry, 1996, vol. 40, pp. 776-784.
Persico, A.M., Vandenbergh, D.J., Smith, S.S., and Uhl, G.R., Dopamine Transporter Gene Polymorphisms Are Not Associated with Polysubstance Abuse, Biol. Psychiatry, 1993, vol. 34, pp. 265-267.
Persico, A.M. and Macciardi, F., Genomic Association between Dopamine Transporter Gene Polymorphisms and Schizophrenia, Am. J. Med. Genet. (Neuropsychiatr. Genet.), 1997, vol. 74, pp. 53-57.
Cook, E.H., Stein, M.A., Krasowski, M.D., et al., Association of Attention-Deficit Disorder and the Dopamine Transporter Gene, Am. J. Med. Genet., 1995, vol. 56, pp. 993-998.
Gill, M., Daly, G., Heron, S., et al., Confirmation of Association between Attention Deficit Hyperactivity Disorder and a Dopamine Transporter Polymorphism, Mol. Psychiatry, 1997, vol. 2, no. 4, pp. 311-313.
Mathew, C.C., The Isolation of High Molecular Weight Eukaryotic DNA, Methods in Molecular Biology, Walker, J.M., Ed., New York: Human, 1984, vol. 2, pp. 31-34.
Roff, D.A. and Bentzen, P., The Statistical Analysis of Mitochondrial DNA: χ2 and Problem of Small Samples, Mol. Biol. Evol., 1989, vol. 6, pp. 539-545.
Sano, A., Kondoh, K., Kakimoto, Y., and Kondo, I., A 40-Nucleotide Repeat Polymorphism in the Human Dopamine Transporter Gene, Hum. Genet., 1993, vol. 91, pp. 405-406.
Li, T., Yang, L., Wiese, C., et al., No Association between Alleles or Genotypes at the Dopamine Transporter Gene and Schizophrenia, Psychiatry Res., 1993, vol. 52, pp. 17-23.
Gelernter, J., Kranzler, H.R., Satel, S.L., and Rao, P.A., Genetic Association between Dopamine Transporter Protein Alleles and Cocaine-Induced Paranoia, Neuropsychopharmacology, 1994, vol. 11, pp. 195-200.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Galeyeva, A.R., Jur'ev, E.B. & Khusnutdinova, E.K. Polymorphism of the Dopamine Transporter Gene in Populations of the Volga–Ural Region. Russian Journal of Genetics 37, 847–849 (2001). https://doi.org/10.1023/A:1016763413404
Issue Date:
DOI: https://doi.org/10.1023/A:1016763413404