Abstract
In experiments conducted on 903 rats, we studied the biometric characteristics of the major salivary glands (parotid, submandibular, and sublingual glands) during ontogenesis. We calculated the indices of nondirectional fluctuation asymmetry for the submandibular and sublingual glands and determined correlation coefficients and the coefficients of linear regression between salivary glands, rat body weight, and the weight of the femoral bone (the largest bone in the rat). The strongest correlation was found between the dry weight of the submandibular gland and the rat body weight. Mathematical analysis of the growth of the submandibular gland after sialotomy allowed us to derive a formula for the quantitative estimation of regeneration, taking into account the natural growth of the rat.
Similar content being viewed by others
REFERENCES
Babaeva, A.G., Postnatal Development of Salivary and Lacrimal Glands in Albino Rats, Byul. Eksp. Biol. Med., 1966, vol. 61, no. 5, pp. 113–115.
Babaeva, A.G., Structural bases of Regeneration and Compensatory Response of Salivary Glands, in Strukturnye osnovy adaptatsii i kompensatsii narushennykh funktsii (Structural Bases of Adaptation and Compensation of Disturbed Functions), Moscow: Nauka, 1987, pp. 191–194.
Bespalov, A.M., Shal'neva, T.V., Kuzina, R.F., and Sokolova, O.A., Changes of Characteristics Describing the Biological Norm in Wistar Rats after Transportation-Induced Stress, in Aktual'nye voprosy standartizatsii laboratornykh zhivotnykh dlya mediko-biologicheskikh issledovanii (Current Problems of Standardization of Laboratory Animals for Medical-Biological Studies), Moscow, 1988, part 1, pp. 11–13.
Denisov, A.B., Mitotic Index in Corneal Epithelium after Alteration of Tissues with Different Proliferative Activity, Byul. Eksp. Biol. Med., 1983, vol. 95, no. 3, pp. 88–89.
Gansburgskii, A.N., Changes of Body Weight of Laboratory Albino Rats during Postnatal Development, Arkh. Anat. Gistol. Embriol., 1989, vol. 97, no. 11, pp. 27–31.
Griffith, Q., The Rat in Laboratory Investigation, Philadelphia, 1942, pp. 28–29.
Kukhling, Kh., Spravochnik po fizike (Handbook on Physics), Moscow: Mir, 1982, pp. 116–117.
Makhin'ko, V.I. and Nikitin, V.N., Growth Constants and Functional Periods of Development of Postnatal Life of Albino Rats, in Molekulyarnye i fiziologicheskie mekhanizmy vozrastnogo razvitiya (Molecular and Physiological Mechanisms of Aging), Kiev: Nauk. Dumka, 1975, pp. 308–326.
Picciarelli, H.M., Oyhenart, E.E., and Ferreros, M.C., Variations of Rat Skull Bone Robusticity Evoked by Malnutrition, Am. J. Phys. Anthropol., 1984, vol. 64, no. 2, pp. 119–124.
Pospelov, V.S. and Korovin, S.V., Devices Providing for Dosed Fasting of Small Laboratory Animals, Patol., Fiziol., Eksper. Terap., 1989, no. 6, pp. 56–57.
Reil, J. and Rother, P., Quntitative und qualitative Aspekte der Darstellung von Alternskurven der Gewebszusammensetzung der menschlichen Unterskurven durch Empirische Regression, Gegenbaurs Morphol. Jahrb., 1984, vol. 130, no. 3, pp. 461–472.
Sepetliev, D., Statisticheskie metody v nauchnykh meditsinskikh issledovaniyakh (Statistical Methods in Scientific Medical Studies), Moscow: Meditsina, 1968, pp. 270–278.
Shornikov, B.S., Dispersion Analysis of the Effect of Partial Hepatectomy on Diversity of the Functional Activity of Parenchymal Rat Liver Cells, in Matematicheskie metody v biologii (Mathematical Methods in Biology), Moscow: Univer. Press, 1972, pp. 91–100.
Strukturnye osnovy adaptatsii i kompensatsii funktsii (Structural Bases of Adaptation and Compensation of Functions), Sarkisov, D.S., Ed., 1987.
Tikhonov, V.N. and Shitikov, V.K., Analysis of Changes of the Weight of Inner Organs in the Toxicological Experiment, Farmakol. Toksikol., 1984, no. 5, pp. 113–116.
Zakharov, V.M., Asimmetriya zhivotnykh (Asymmetry in Animals), Moscow: Nauka, 1987, pp. 42–46.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Denisov, A.B. Use of Biometric Characteristics of Major Salivary Glands as a Baseline to Develop a Formula for the Quantitative Estimation of Posttraumatic Regeneration of Glandular Tissue. Russian Journal of Developmental Biology 32, 215–220 (2001). https://doi.org/10.1023/A:1016711017193
Issue Date:
DOI: https://doi.org/10.1023/A:1016711017193