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Study of Thresholds of Motor Evoked Responses during Transcranial Magnetic Stimulation in Healthy Subjects and Patients with Brain Tumors

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Abstract

Since 1985, transcranial magnetic stimulation (TMS) has been widely used for the investigation of different processes in the human central nervous system. We studied the thresholds of the motor-evoked responses (MER) during TMS and their hemispheric differences in healthy subjects and patients with brain tumors of different localization: in the brainstem projection, left and right motor areas, and left frontal-temporal area. The obtained results testify to a lower threshold of MER in healthy subjects during TMS of the dominant hemisphere. In patients with brainstem tumors, there was a decrease in the thresholds of MER during TMS. In patients with tumors in the motor area, the thresholds of MER were increased on the lesion side, whereas in patients with tumors in the left temporal area, the thresholds were significantly decreased during TMS of the lesioned hemisphere.

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  1. Burdenko Institute of Neurosurgery, Russian Academy of Medical Sciences, 4-ya Tverskaya-Yamskaya ul. 16, Moscow, 125047, Russia

    R. F. Gimranov

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  1. R. F. Gimranov
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Gimranov, R.F. Study of Thresholds of Motor Evoked Responses during Transcranial Magnetic Stimulation in Healthy Subjects and Patients with Brain Tumors. Human Physiology 28, 413–416 (2002). https://doi.org/10.1023/A:1016573713772

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