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Sandhoff disease in a golden retriever dog

  • Published:
Journal of Inherited Metabolic Disease

Abstract

A golden retriever dog is described with total hexosaminid ase deficiency and raised GM2-ganglioside in CSF. The animal represents a model for human Sandhoff disease.

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REFERENCES

  • Gravel RA, Kaback MM, Proia RL, Sandhoff K, Suzuki K, Suzuki K (2000) The GM2 gangliosidosis. In Scriver CR, Beaudet AL, Sly WS, Valle D, eds.; Childs B, Kinzler KW, Vogelstein B, assoc. eds. The Metabolic and Molecular Bases of Inherited Disease, 8th edn. New York: McGraw-Hill, 3827-3876.

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Authors and Affiliations

  1. Laboratory of Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan

    O. Yamato, H. Satoh, M. Yamasaki & Y. Maede

  2. Department of Veterinary Clinical Pathology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Tokyo, Japan

    N. Matsuki, M. Inaba & K. Ono

Authors
  1. O. Yamato
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  2. N. Matsuki
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  3. H. Satoh
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  4. M. Inaba
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  5. K. Ono
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  6. M. Yamasaki
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  7. Y. Maede
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Corresponding author

Correspondence to O. Yamato.

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Yamato, O., Matsuki, N., Satoh, H. et al. Sandhoff disease in a golden retriever dog. J Inherit Metab Dis 25, 319–320 (2002). https://doi.org/10.1023/A:1016562626961

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  • DOI: https://doi.org/10.1023/A:1016562626961

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