Skip to main content
SpringerLink
Log in

Neurophysiological and Neuropsychological Indicators of the Efficiency of the Rehabilitation of Patients with Parkinsonism

  • Published:
Human Physiology Aims and scope Submit manuscript

Abstract

This work experimentally showed the possibility of using neurophysiological and neuropsychological indicators of the efficiency of rehabilitation to better understand brain mechanisms of the syndrome and the compensation of deficiencies using a model of rehabilitation of motor and cognitive functions in patients with Parkinson's disease. A study paradigm was developed in three patients with a predominantly akinetic–rigid form of parkinsonism. The methods of the study included clinical neurological, neuropsychological, neurophysiological, and psychometric analyses. A positive correlation was found between clinical, psychometric, and neuropsychological measures, and a positive correlation between neurophysiological and neuropsychological measures was found only in the subject with the minimum dysfunction in this group, with the shortest period of illness, and predominantly right-hemispheric lateralization of the processes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. Bernstein, N.A., Ocherki fiziologii dvizhenii i fiziologii aktivnosti, (Essays on the Physiology of Movements and Physiology of Activity), Moscow, 1966.

  2. Anokhin, P.K., Biologiya i neirofiziologiya uslovnogo refleksa (Biology and Neurophysiology of the Conditioned Reflex), Moscow, 1968.

  3. Luria, A.R., Vysshiye korkoviye funktsii cheloveka, izd. 2 (Higher Cortical Functions of the Man, 2nd ed.), Moscow: Moscow Gos. Univ., 1969.

    Google Scholar 

  4. Luria, A.R., Mozg cheloveka i psikhicheskiye protsessy (Human Brain and Mental Processes), Moscow: APN SSSR, 1970, vol. 2.

    Google Scholar 

  5. Luria, A.R., Osnovy neiropsikhologii (Basic Neuropsychology), Moscow: Moscow Gos. Univ., 1973.

    Google Scholar 

  6. Khomskaya, E.D., Mozg i aktivatsiya (Brain and Arousal), Moscow: Moscow Gos. Univ., 1972.

    Google Scholar 

  7. Sokolov, E.N., Psikhofiziologiya pamyati (Psychophysiology of Memory), Moscow, 1974.

  8. Pribram, K., Yazyki mozga (The Languages of the Brain), Moscow, 1975.

  9. Farber, D.A., Beteleva, T.G., Dubrovinskaya, N.V., and Machinskaya, R.I., Neurophysiological Bases of the Dynamic Localization of Functions in the Organism, 1 Mezhdunar. Konf. Pamyati A.R. Luria (First Int. Conf. Memory of A.R. Luria), Moscow: RPO, 1998, p. 208.

    Google Scholar 

  10. Golubev, V.L., Levin, Ya.I., and Vein, A.M., Bolezn' Parkinsona i sindrom parkinsonizma (The Parkinson's Disease and the Parkinsonism Syndrome), Moscow: MED press, 1999.

    Google Scholar 

  11. Lobniye doli i regulyatsiya psikhicheskikh protsessov (The Frontal Lobe and the Regulation of Mental Processes), Luria, A.R. and Khomskaya, E.D., Eds., Moscow: Moscow Gos. Univ., 1966.

    Google Scholar 

  12. Fahn, S. and Elton, R., nified Parkinson's Disease Rating Scale. Version 3, in Recent Development in Parkinson's Disease, Fahn, S., Marsden, C., Calne, D.,et al., Eds., New York, 1987.

  13. Glozman, Zh.M., Kolichestvennaya otsenka dannykh neiropsikhologicheskogo obsledovaniya (Quantitative Assessment of Neuropsychological Examination Data), Moscow: Tsentr Lechebnoi Pedagogiki, 1999.

    Google Scholar 

  14. Gilden, L., Vaugham, H.G., and Costa, L.D., Summated Human Electroencephalographic Potentials Associated with Voluntary Movement, EEG. Clin. Neurophysiol., 1966, vol. 20, p. 433.

    Google Scholar 

  15. Vein, A.M., Vendrova, M.I., and Tabeeva, G.R., The Motor Potential (A Review), Zh. Nevrol. Psikhiatr. im. S.S. Korsakova, 1999, no. 9, p. 56.

    Google Scholar 

  16. Papacostopoulos, D., Banerji, N.K., and Pocock, P.V., Performance, EMG, Brain Electrical Potentials and Heart Rate Change During Self-Paced Skilled Motor Task in Parkinson's Disease, J. Psychophysiol., 1990, vol. 4, p. 163.

    Google Scholar 

  17. Vendrova, M.I., Sadekov, R.A., and Tabeeva, G.R., Using the Rapidly Acting Madopar for Prediction of the Efficiency of L-DOPA Medications, Sb. Dokl. Nauch.- praktich. Konf. “Bolezn' Parkinsona” (Proc. Sci.-Pract. Conf. “The Parkinson's Disease”), Moscow, 1999, p. 27.

  18. Beck, A.T., Ward, C.H., Mendelson, M. et al., An Inventory for Measuring Depression, Arch. Gen. Psychiatry, 1961, vol. 4, p. 561.

    Google Scholar 

  19. Pylaeva, N.M. and Akhutina, T.V., Shkola vnimaniya (School of Attention), Moscow: INTOR, 1997.

    Google Scholar 

  20. Deecke, L., Grozinger, B., Kornhuber, H.H., et al., Brain Potentials Associated with Voluntary Manual Tracking: Bereitschatspotential, Conditioned Premotion Positivity (cPMP), Directed Attention Potential (DAP), and Relaxation Potential (RXP), in Anticipatory Activity of the Limbic and Frontal Cortex, Ann. N.Y. Acad. Sci. Brain and Information Event-Related Potential, Karrer et al., Eds., New York, 1984a, vol. 425, p. 444.

    Google Scholar 

  21. Hilljard, S.A., The CNV and Human Behaviour: A Review, EEG and Clin. Neurophysiol., 1973, vol. 33, p. 161.

    Google Scholar 

  22. Naatanen, R. and Michie, P.T., Different Variants of Endogenous Negative Brain Potentials in Performance Situations: A Review and Classifications, in Human Evoked Potentials, New York: Plenum, 1979, p. 251.

    Google Scholar 

  23. Kutas, M. and Donchin, E., The Effect of Handedness of Responding Hand, and of Response Force on the Contralateral Dominance of the Readiness Potential, in Attention, Voluntary Contraction and Event-Related Cerebral Potentials, Desmedt, J.E., Ed., Basel, 1977, p. 189.

  24. Deecke, L., Grozinger, B., Komhuber, H.H., et al., Cerebral Potential Related to Voluntary Movement, Speech Production, and Respiration in Man, Origin of Cerebral Field Potentials: Intern. Symp. Muenster, FRG, Specman, E.S. And Caspers, H., Eds., Stuttgart, 1979, p. 132.

  25. Grozinger, B., Komhuber, H.H., Kriebel, J., et al., The Bereitschaftspotential Preceding the Act of Speaking. Also an Analysis of Artifacts, in Motivation, Motor and Sensory Processes of the Brain: Electrical Potentials, Behaviour and Clinical Use, Komhuber, H.H and Deecke, L., Eds., Amsterdam, 1980. p. 798.

  26. Gebrandt, L.K., Goff, W.R, and Smith, D.B., Distribution of the Human Average Movement Potential, EEG and Clin. Neurophysiol., 1973, vol. 34, p. 461.

    Google Scholar 

  27. Iwase, K., A Study of the Readiness Potential, EEG and Clin. Neurophysiol., 1975, vol. 39, p. 543.

    Google Scholar 

  28. Deecke, L., Sheild, P., and Kornhuber, H.H., Distribution of Redness Potential, Premotion Positivity, and Motor Potential of the Human Cerebral Cortex Preceding Voluntary Finger Movements, Exp. Brain Res., 1969, vol. 7, p. 158.

    Google Scholar 

  29. Vygotsky, L.S., O psikhologicheskikh sistemakh, (On Psychological Systems) in Sobranie sochinenii v 6 tomakh (Collected Works in 6 vols.), Moscow, 1982, vol. 1.

  30. Luria, A.R., Vosstanovlenie funktsii mozga posle voennoi travmy (Recovery of Brain Function after Military Trauma), Moscow: Akad. Med. Nauk SSSR, 1948.

    Google Scholar 

  31. Glozman, Zh.M. and Bicheva, K.G., Neuropsychological Correction of Step Deficits at the Parkinson's Disease, Vestn. MGU, ser. 14, Psikhologiya, 1999, no. 1, p. 31.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sechenov Moscow Medical Academy, Moscow

    M. I. Vendrova & R. A. Sadekov

  2. Moscow State University, Vorob'evy Gory, Moscow, 119899, Russia

    Zh. M. Glozman & S. Yu. Ignat'eva

Authors
  1. M. I. Vendrova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zh. M. Glozman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. Yu. Ignat'eva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. A. Sadekov
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vendrova, M.I., Glozman, Z.M., Ignat'eva, S.Y. et al. Neurophysiological and Neuropsychological Indicators of the Efficiency of the Rehabilitation of Patients with Parkinsonism. Human Physiology 28, 391–397 (2002). https://doi.org/10.1023/A:1016517528793

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1016517528793

Keywords

Search

Navigation