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Reasons for Structure-Acid Resistance Correlation in Series of Substituted Phenylpenicillins

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Abstract

The kinetics of acid hydrolysis of phenylpenicillins substituted in the benzene ring were studied at pH 3.0 and temperatures of 20, 25, and 30°C. A Hammett correlation analysis of the reaction was performed.

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Authors and Affiliations

  1. Russian Academy of Sciences, Institute of Macromolecular Compounds, St. Petersburg, Russia

    M. V. Solovskii & G. Yu. Pek

  2. Russian Academy of Sciences, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia

    M. V. Solovskii & G. Yu. Pek

Authors
  1. M. V. Solovskii
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  2. G. Yu. Pek
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Solovskii, M.V., Pek, G.Y. Reasons for Structure-Acid Resistance Correlation in Series of Substituted Phenylpenicillins. Russian Journal of Applied Chemistry 75, 281–285 (2002). https://doi.org/10.1023/A:1016172722206

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  • DOI: https://doi.org/10.1023/A:1016172722206

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