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Markers of General Pathology

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Abstract

Studies of the protein composition of leukocytes revealed markers of general pathology: 2 protein parameters (53K/H2A>0.25; 43K/H2A<1.61) differed from normal in 1627 patients with various pathologies. We compared protein parameters of leukocytes with other markers of general pathology. By the sensitivity and spectrum of associated diseases, the detected protein parameters of leukocytes can serve as the gold standard in the diagnostics of general pathology. These protein markers can be used for screening of newborns requiring therapeutic and preventive treatment, employers exposed to occupational hazards, and people inhabiting ecologically unfavorable regions, and for prevention of therapeutic complications in patients.

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Authors and Affiliations

  1. Medical and Genetic Research Center, Russian Academy of Medical Sciences, Moscow

    V. D. Paponov, V. V. Paponov & G. V. Baidakova

Authors
  1. V. D. Paponov
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  2. V. V. Paponov
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  3. G. V. Baidakova
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Correspondence to V. D. Paponov.

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Paponov, V.D., Paponov, V.V. & Baidakova, G.V. Markers of General Pathology. Bulletin of Experimental Biology and Medicine 133, 222–224 (2002). https://doi.org/10.1023/A:1015866129473

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  • DOI: https://doi.org/10.1023/A:1015866129473

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