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Photoquenching of the Bioluminescence of the Genetically Engineered Escherichia coli TG1 (pXen7) Strain in the Presence of Photodithazine

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Abstract

The photoquenching of the bioluminescence of the genetically engineered Escherichia coli TG1 (pXen7) strain was studied in the presence of the photosensitizer photodithazine, a glucosamine salt of chlorin e 6. The photosensitized quenching of the bioluminescence was found to correlate with the colony-forming ability of the strain. The data obtained are discussed from the standpoint of using biosensor luminescent bacterial systems for the assessment of the efficiency of photosensitizers in antimicrobial photochemotherapy.

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Strakhovskaya, M.G., Parkhomenko, I.M., Rumbal', Y.V. et al. Photoquenching of the Bioluminescence of the Genetically Engineered Escherichia coli TG1 (pXen7) Strain in the Presence of Photodithazine. Microbiology 71, 294–297 (2002). https://doi.org/10.1023/A:1015850510644

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