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Pharmacokinetics of Droperidol in Healthy Volunteers Following Intravenous Infusion and Rectal Administration from an Osmotic Drug Delivery Module

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REFERENCES

  1. S. K. Pandit, S. P. Kothary, U. A. Pandit, G. Randel, and L. Levy. Dose response study of droperidol and metoclopramide as antiemetics for outpatient anesthesia. Anesth. Analg. 68:798–802 (1989).

    Google Scholar 

  2. M. Fischler, F. Bonnet, H. Tarang, L. Jacob, J. C. Levron, B. Flaisler, and G. Vourc'h. The pharmacokinetics of droperidol in anesthetized patients. Anesthesiology 64:486–489 (1986).

    Google Scholar 

  3. Physicians' Desk Reference, 44th ed., Medical Economics Co., Oradell, NJ, 1990, p. 1084.

  4. A. G. de Boer, F. Mooenaar, L. D. J. de Leede, and D. D. Breimer. Rectal drug administration: Clinical pharmacokinetic considerations. Clin. Pharmacokin. 7:285–311 (1982).

    Google Scholar 

  5. F. Theeuwes. Rate controlled delivery by the oral and rectal route. In D. Breimer and P. Speiser (eds.), Topics in Pharmaceutical Sciences, Elsevier, Science, Amsterdam, 1985, pp.119–132.

    Google Scholar 

  6. F. Theeuwes. Elementary osmotic pump. J. Pharm. Sci. 64:1987–1991 (1975).

    Google Scholar 

  7. N. Watari and L. Z. Benet. Determination of mean input time, mean residence time, and steady state volume of distribution with multiple drug inputs. J. Pharmacokin. Biopharm. 17:593–599 (1989).

    Google Scholar 

  8. W. A. Cressman, J. Plostnieks, and P. C. Johnson. Absorption, metabolism and excretion of droperidol by human subjects following intramuscular and intravenous administration. Anesthesiology 38:363–369 (1973).

    Google Scholar 

  9. R. Bevilacqua, C. A. Benassi, R. Largajolli, and I. M. Veronese. Psychoactive butyrophenones: Binding to human and bovine serum albumin. Pharmacol. Res. Commun. 11:447–454 (1979).

    Google Scholar 

  10. M. Gibaldi and D. Perrier. Pharmacokinetics, Marcel Dekker, New York, 1982.

    Google Scholar 

  11. J. G. Wagner. Pharmacokinetic absorption plots from oral data alone or oral/intravenous data and an exact Loo-Riegelman equation. J. Pharm. Sci. 72:838–842 (1983).

    Google Scholar 

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  1. ALZA Corporation, Palo Alto, California, 94303

    Suneel K. Gupta, Mary Southam & Stephen Hwang

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  1. Suneel K. Gupta
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  2. Mary Southam
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  3. Stephen Hwang
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Gupta, S.K., Southam, M. & Hwang, S. Pharmacokinetics of Droperidol in Healthy Volunteers Following Intravenous Infusion and Rectal Administration from an Osmotic Drug Delivery Module. Pharm Res 9, 694–696 (1992). https://doi.org/10.1023/A:1015822715190

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