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Structure-Activity Relationship of Insecticidal Steroids. IV. 3β-Chlorosubstituted Derivatives of Cholesterol and β-Sitosterol

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Abstract

The toxicity of 3β-chlorosteroids 1-8 for colorado beetle (Leptinotarsa decemlineata Say.) larvae was studied by a contact-intestinal method. The most active insect growth and development regulators of the studied compounds are 3β-chlorocholest-5-ene (1a), 3β-chloro-5α,6β-diol 6-formate (3b), 3β-chloro-7α-hydroxy-6-ketone (4a), and 3β-chloro-5α-bromo-Δ4-6-ketone (8).

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REFERENCES

  1. S. A. Tarlakovskii, Tr. VNII Zashchity Rast., No. 52, 53–65 (1977).

  2. N. V. Kovganko and A. A. Akhrem, Steroids: Ecological Functions [in Russian], Nauka i Tekhnika, Minsk (1990).

    Google Scholar 

  3. A. A. Akhrem and N. V. Kovganko, Ecdysteroids: Chemistry and Biological Activity [in Russian], Nauka i Tekhnika, Minsk (1989).

    Google Scholar 

  4. A. A. Akhrem, F. A. Lakhvich, V. A. Khripach, N. V. Kovganko, A. I. Bykhovets, and A. M. Guk, USSR Pat. No. 1110150, Byull. Izobret., No. 43–44, 187 (1993); Chem. Abstr., 123, 228649n (1995).

    Google Scholar 

  5. A. A. Akhrem, F. A. Lakhvich, V. A. Khripach, N. V. Kovganko, A. I. Bykhovets, and S. L. Bykhovets, USSR Pat. No. 1266167, Byull. Izobret., No. 43–44, 187–188 (1993); Chem. Abstr., 123, 228643f (1995).

    Google Scholar 

  6. A. A. Akhrem, F. A. Lakhvich, V. A. Khripach, N. V. Kovganko, A. I. Bykhovets, and S. L. Bykhovets, USSR Pat. No. 1309350, Byull. Izobret., No. 43–44, 187 (1993); Chem. Abstr., 123, 278723c (1995).

    Google Scholar 

  7. S. L. Bykhavets, R. M. Zalatar, and A. I. Bykhavets, Vestsi Akad. Navuk BSSR, Ser. Biyal. Navuk, No. 1, 54 (1995).

  8. N. V. Kovganko and S. N. Sokolov, Khim. Prir. Soedin., 617 (1999).

  9. N. V. Kovganko and S. N. Sokolov, Khim. Prir. Soedin., 470 (2000).

  10. N. V. Kovganko and S. N. Sokolov, Khim. Prir. Soedin., 388 (2001).

  11. R. M. Zolotar′, A. I. Bykhovets, and N. V. Kovganko, Khim. Prir. Soedin., 460 (2001).

  12. R. M. Zolotar′, A. I. Bykhovets, S. N. Sokolov, and N. V. Kovganko, Khim. Prir. Soedin., 462 (2001).

  13. R. M. Zolotar′, A. I. Bykhovets, S. N. Sokolov, and N. V. Kovganko, Khim. Prir. Soedin., 54 (2002).

  14. K. Schreiber, G. Osske, and G. Sembdner, Experientia, 17, No. 10, 463 (1961).

    Google Scholar 

  15. N. V. Kovganko, D. V. Drozdov, and S. K. Ananich, Khim. Prir. Soedin., 94 (1999).

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, 220141, Minsk, ul. Akad. Kuprevicha, 5/2

    R. M. Zolotar', A. I. Bykhovets, S. N. Sokolov & N. V. Kovganko

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  1. R. M. Zolotar'
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  2. A. I. Bykhovets
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  3. S. N. Sokolov
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  4. N. V. Kovganko
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Zolotar', R.M., Bykhovets, A.I., Sokolov, S.N. et al. Structure-Activity Relationship of Insecticidal Steroids. IV. 3β-Chlorosubstituted Derivatives of Cholesterol and β-Sitosterol. Chemistry of Natural Compounds 38, 70–73 (2002). https://doi.org/10.1023/A:1015789917352

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