Abstract
Oxidation of betulin by pyridinium dichromate, pyridinium chlorochromate, and K2Cr2O7 -H2SO4 in the presence of tetrabutylammonium bromide was studied. Products of regioselective C-3, C-28-, and exhaustive oxidation, 28-hydroxylup-20(29)-3-one, 3β-hydroxy- and 3-oxolup-20(29)-en-28-al were obtained.
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Komissarova, N.G., Belenkova, N.G., Spirikhin, L.V. et al. Selective Oxidation of Betulin by Cr(VI) Reagents. Chemistry of Natural Compounds 38, 58–61 (2002). https://doi.org/10.1023/A:1015733832373
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DOI: https://doi.org/10.1023/A:1015733832373