Abstract
Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP- syndrome. Different disturbances of large- and small-scale saccades were found.
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REFERENCES
Yu. V. Burov, S. E. Metkalova, A. E. Kustov, et al., Byull. Eksp. Biol. Med., 114, No. 11, 495–497 (1992).
Yu. V. Burov, V. V. Shul'govskii, G. V. Petrov, et al., Ros. Fiziol. Zh., 81, No. 10, 109–112 (1995).
A. V. Latanov, L. V. Tereshchenko, A. G. Yudin, V. V. Shul'-govskii, Ibid., 83, Nos. 1–2, 155–158 (1997).
L. V. Tereshchenko, Asymmetry of Saccadic Parameters and Hand Movements in Monkeys under Normal and Pathologic Conditions, Abstract of Cand. Med. Sci. Dissertation, Moscow (1999).
L. V. Tereshchenko, Yu. B. Kuznetsov, A. V. Latanov, and V. V. Shul'govskii, Zh. Vyssh. Nervn. Deyat., 50, No. 5, 889–894 (2000).
V. V. Shul'govskii, A. V. Latanov, and G. V. Petrov, Vestn. Ross. Akad. Med. Nauk, 1, No. 1, 49–52 (1994).
C. E. Clarke, M. A. Sambrook, I. J. Mitchell, and A. R. Crossman, J. Neurol. Sci., 78, No. 3, 273–280 (1987).
D. A. Robinson, IEEE Trans. Biomed. Eng., BME-10, 137–145 (1963).
J. S. Schneider and C. J. Kovelowski, Brain Res., 519, No. 1–2, 122–128 (1990).
J. R. Taylor, J. D. Elsworth, R. H. Roth, et al., Brain, 113, No. 3, 617–637 (1990).
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Tereshchenko, L.V., Yudin, A.G., Kuznetsov, Y.B. et al. Disturbances of Saccadic Eye Movements in Monkeys during Development of MPTP-Induced Syndrome. Bulletin of Experimental Biology and Medicine 133, 182–184 (2002). https://doi.org/10.1023/A:1015563225510
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DOI: https://doi.org/10.1023/A:1015563225510