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Immunomodulation of Inherent Behavior in C57Bl/6 and BALB/c Mice with Antibodies to Glutamate

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Abstract

Immunization of BALB/c mice with glutamate-BSA conjugate reduced anxiety and improved passive avoidance retention, while in C57Bl/6 mice immunization disturbed passive avoidance retention, but had no effect on anxiety. Interstrain differences in the shuttle box behavior were found between control animals.

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Authors and Affiliations

  1. Laboratory of Neuroimmunopathology, Institute of General Pathology and Pathological Physiology, Russian Academy of Medical Sciences, Moscow

    N. A. Trekova, O. I. Mikovskaya, L. A. Basharova, L. A. Vetrile & V. A. Evseev

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  1. N. A. Trekova
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  2. O. I. Mikovskaya
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  3. L. A. Basharova
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  4. L. A. Vetrile
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  5. V. A. Evseev
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Trekova, N.A., Mikovskaya, O.I., Basharova, L.A. et al. Immunomodulation of Inherent Behavior in C57Bl/6 and BALB/c Mice with Antibodies to Glutamate. Bulletin of Experimental Biology and Medicine 133, 118–121 (2002). https://doi.org/10.1023/A:1015522116423

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  • DOI: https://doi.org/10.1023/A:1015522116423

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