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Chemistry of Heterocyclic Compounds

, Volume 38, Issue 2, pp 231–237 | Cite as

Cyclocondensation of 2-Amino-1,3,4-thiadiazoles with β-Sulfonylvinyltrifluoromethyldiols

  • A. L. Krasovsky
  • A. M. Moiseev
  • V. G. Nenajdenko
  • E. S. Balenkova
Article

Abstract

A series of CF3-containing 6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-ols was obtained by the interaction of 2-amino-1,3,4-thiadiazoles with β-sulfonylvinyltrifluoromethyldiols and their stereochemistry was established. The structure of 5-(phenylsulfonyl)-7-(trifluoromethyl)-6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-ol was confirmed by X-ray crystallography.

2-amino-1,3,4-thiadiazoles 6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidines β-sulfonylvinyltrifluoromethyldiols cyclocondensation 

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Copyright information

© Plenum Publishing Corporation 2002

Authors and Affiliations

  • A. L. Krasovsky
    • 1
  • A. M. Moiseev
    • 1
  • V. G. Nenajdenko
    • 1
  • E. S. Balenkova
    • 1
  1. 1.M. V. Lomonosov Moscow State UniversityMoscow

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