Abstract
Interleukin-1beta mRNA, interleukin-1beta receptor mRNA, and erythropoietin receptor mRNA are expressed in the brain of (CBA×C57Bl)F1 mice. Immunization with sheep erythrocytes stimulated the expression of these cytokines in the cerebral hemispheres. Injection of recombinant erythropoietin reduced expression of interleukin-1beta, interleukin-1beta receptor, and erythropoietin receptor genes in the brain of experimental animals and considerably increased their motor activity in the open field test.
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Poveshchenko, A.F., Markova, E.V., Korotkova, N.A. et al. Cytokine Gene Expression in Cerebral Hemispheres and Behavioral Reactions of (CBA×C57Bl)F1 Mice. Bulletin of Experimental Biology and Medicine 133, 65–67 (2002). https://doi.org/10.1023/A:1015112729103
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DOI: https://doi.org/10.1023/A:1015112729103