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Delayed Effects of 1,2-Epoxypropyltrimethylammonium Chloride on Behavioral Reactions in Rats

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Abstract

We studied immediate and delayed effects of intraventricular injection of 1,2-epoxypropyltrimethylammonium chloride on behavioral reactions in rats. Apomorphine-induced yawning increased and orientation and exploratory activity was improved 144 h postinjection, which indicates activation of the brain dopaminergic system during this period.

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Authors and Affiliations

  1. Laboratory of Bioscreening, ASINEKS Company; Department of Toxicology and Trials of Drug Compounds, All-Russian Research Center of Molecular Diagnosis and Treatment, Moscow

    Yu. G. Plyashkevich & G. G. Barsegyan

Authors
  1. Yu. G. Plyashkevich
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  2. G. G. Barsegyan
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Plyashkevich, Y.G., Barsegyan, G.G. Delayed Effects of 1,2-Epoxypropyltrimethylammonium Chloride on Behavioral Reactions in Rats. Bulletin of Experimental Biology and Medicine 133, 51–53 (2002). https://doi.org/10.1023/A:1015104427286

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  • DOI: https://doi.org/10.1023/A:1015104427286

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